Abnormal Spontaneous Regional Brain Activity in Young Patients With Anorexia Nervosa

Functional MRI studies have repeatedly shown alterations in patients with anorexia nervosa (AN). These alterations might be driven by baseline signal characteristics such as the (fractional) amplitude of low frequency fluctuations (fALFF/ALFF), as well as regional signal consistency [ie. regional homogeneity (ReHo)] within circumscribed brain regions. Previous studies have also demonstrated grey matter (pseudo-) atrophy in underweight AN. Here we study fALFF/ALFF and ReHo in predominantly adolescent patients with AN, while taking grey matter changes into consideration.
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: New Research Source Type: research