The reduction of apnea-hypopnea duration ameliorates endothelial dysfunction, vascular inflammation, and systemic hypertension in a rat model of obstructive sleep apnea.

CONCLUSIONS: Longer apnea-hypopnea duration is related to more systemic inflammatory and endothelial dysfunction, and hypertension and cardiac remodeling. These can be reversed after a period of recovery, which indicates that time parameters for assessing OSA, such as apnea-hypopnea duration, should be considered instead of apnea-hypopnea index only.
PMID: 30762174 [PubMed - as supplied by publisher]

Source: Sleep and Breathing - February 14, 2019 Category: Sleep Medicine Authors: Wu H, Lv Q, Zhang H, Qin Y, Fang F, Sun H, Wei Y Tags: Sleep Breath Source Type: research