Waterborne pharmaceutical uptake and toxicity is modified by pH and dissolved organic carbon in zebrafish

In conclusion, the influence of pH and DOC on drug uptake and toxicity in fish appears to be predictable based on the physicochemical properties of the drug (e.g. pKa, polar surface area). The influence of water chemistry on drug bioavailability in fish is likely relevant to all aquatic life.
Source: Aquatic Toxicology - Category: Toxicology Source Type: research