Sleep Characteristics and Cognitive Function and Decline Among Older Adults.

Sleep Characteristics and Cognitive Function and Decline Among Older Adults. Am J Epidemiol. 2019 Feb 13;: Authors: McSorley VE, Bin YS, Lauderdale DS Abstract Sleep laboratory studies find that restricted sleep duration leads to worse short-term cognition, especially memory. Observational studies find associations between self-reported sleep duration or quality and cognitive function. However self-reported sleep characteristics may not be very accurate and misreporting could relate to cognition. In the Sleep Study of the National Social Life, Health, and Aging Project (NSHAP), a nationally-representative cohort of US older adults (2010-2015), we examine whether self-report and actigraph measured sleep are associated with cross-sectional cognitive function and 5-year cognitive decline. Cognition is measured with the survey adaption of the multidimensional Montreal Cognitive Assessment (MoCA-SA). At baseline (n = 759), average MoCA-SA was 14.1 of 20 (SD, 3.6). In cross-sectional models, actigraph sleep disruption measures (wake after sleep onset, fragmentation, percent sleep, wake bouts) were associated with worse cognition. Sleep disruption measures were standardized, and estimates of association were similar (range, -0.37 to -0.59 MoCA-SA point per SD of disruption). Actigraph sleep disruption measures were also associated with odds of 5-year cognitive decline (4 or more points), with wake after sleep onset having the strongest as...
Source: Am J Epidemiol - Category: Epidemiology Authors: Tags: Am J Epidemiol Source Type: research