Osteocalcin (bone GLA protein) levels, vascular calcifications, vertebral fractures and mortality in hemodialysis patients with diabetes mellitus.

CONCLUSIONS: HD patients have an increased mortality risk associated with DM. Furthermore, we found an association between DM and decreased BGP levels. Although our study does not support the notion that BGP levels act as mediator in the DM-mortality link, to our knowledge this is the first study in HD patients suggesting a potential protective role of BGP in the bone, endocrine and vascular pathway.
PMID: 30759309 [PubMed - as supplied by publisher]

Source: Journal of Nephrology - February 13, 2019 Category: Urology & Nephrology Authors: Fusaro M, Gallieni M, Aghi A, Rizzo MA, Iervasi G, Nickolas TL, Fabris F, Mereu MC, Giannini S, Sella S, Giusti A, Pitino A, D'Arrigo G, Rossini M, Gatti D, Ravera M, Di Lullo L, Bellasi A, Brunori G, Piccoli A, Tripepi G, Plebani M Tags: J Nephrol Source Type: research