Dr. Mags Portman, HIV Prevention Pioneer, Dies from Mesothelioma at 44

Dr. Mags Portman, a British trailblazer in the fight to prevent and control HIV, died Wednesday after a two-year battle with mesothelioma. She was 44. Portman was lauded for triggering a significant reduction in HIV diagnoses throughout the United Kingdom by her work as a researcher, clinician and outspoken advocate. She earned international acclaim for her work as an HIV consultant at London’s Mortimer Market Centre, a progressive sexual health clinic that made pre-exposure prophylaxis (PrEP) a reality in the U.K. Portman played a key role in the 2014 study at The Royal London Hospital that proved the efficacy of the drug Truvada, which became part of PrEP and the fight against HIV in England. She was a leader in educating activists and caregivers about the lifesaving potential of PrEP. When the National Health Service delayed its approval of Truvada, Portman worked tirelessly in connecting patients and doctors to online resources and provide access to generic and affordable forms of the medication. “We’re heartbroken at the loss of Dr. Mags Portman, who was a hero and an inspiration to the HIV/AIDS advocacy community,” wrote the Elton John AIDS Foundation on the charity’s Twitter account. “Her legacy — proving the efficacy of PrEP and making it so much more accessible internationally — continues in the lives she helped save.” Mesothelioma UK, a national charity group, shared their condolences on Twitter. Mesothelioma ...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news

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Authors: Turan AS, Ultee G, Van Geenen EJM, Siersema PD Abstract INTRODUCTION: The most commonly used treatment for advanced colorectal adenomas is endoscopic mucosal resection (EMR). The increased number of EMRs since the introduction of the screening program for colorectal cancer has resulted in an increase in EMR-related complications. This review summarizes the current knowledge for the use of clips for the treatment and prevention of complications after EMR. Areas covered: The historical development of clips is summarized and their properties are evaluated. An overview is presented of the evidence for therapeu...
Source: Expert Review of Medical Devices - Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research
Chem. Commun., 2019, Advance Article DOI: 10.1039/C9CC01506J, CommunicationYuan Ma, Quanbing Mou, Lijuan Zhu, Yue Su, Xin Jin, Jing Feng, Deyue Yan, Xinyuan Zhu, Chuan Zhang Polygemcitabine nanogels assembled from DNA-like polygemcitabine undergo rapid intracellular degradation to generate active gemcitabine derivatives for enhanced cancer therapy. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
AbstractObjectiveTo evaluate factors associated with use of patient navigation in a prostate cancer population and identify whether navigation is associated with prolonged  time to care. Cancer patient navigation has been shown to improve access to cancer screening, diagnosis, and treatment, but little is known about patient navigation in prostate cancer care.MethodsAll men diagnosed with localized prostate cancer between 2009 and 2015 were abstracted from the MaineHealth  multi-specialty tumor registry. Regression analyses controlling for patient-, disease-, and system-level factors evaluated characteristics ass...
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
ConclusionIn conclusion, this study illustrates that the application and benefits of HS on reducing GI rectal dose endpoints and toxicities during prostate cancer RT can be reliably replicated in a community setting similar to centres participating in the randomised trial under high quality assurance trial monitoring.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
ConclusionThere is a need to enhance a constant patient –HCP dialogue, and both groups need to make a conscious effort in that direction. This would help in increasing patients’ awareness of risks, having better treatment choice and acceptance, and reducing side-effects.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
(copied from reddit) Hey guys, So I wanted to follow up on a previous thread I started, which discussed some obstacles and hardships I faced as an undergrad, which included losing my mom to cancer over the course of 2 years. In short, this left me broken mentally, physically, and a scar on my academic career. My GPA was significantly impacted and it decreased incredibly through those years, however, the past 3... What to do next? Graduate and kind of lost right now
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Nontraditional Students Source Type: forums
Conclusions This review describes how leukocyte-heparanase can be a double-edged sword in tumor progression; it can enhance tumor immune surveillance and tumor cell clearance, but also promote tumor survival and growth. We also discuss the potential of using heparanase in leukocyte therapies against tumors, and the effects of heparanase inhibitors on tumor progression and immunity. We are just beginning to understand the influence of heparanase on a pro/anti-tumor immune response, and there are still many questions to answer. How do the pro/anti-tumorigenic effects of heparanase differ across different cancer types? Does...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Conclusions Epidemiological studies have repeatedly helped identify definitive triggers for several diseases. As highlighted in this perspective report, previous studies strongly argue for the interplay between intrinsic factors and putative preventable extrinsic triggers/promoters for CTCL. Given the evidence of geographical regional clustering of CTCL patients, CTCL occurrence in unrelated family members and recent evidence implicating S. aureus in the pathogenesis/progression of CTCL, more research is needed to decipher the precise mechanism by which specific environmental exposures may be driving the pathogenesis of t...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
The separation of benign from malignant mesothelial proliferations is crucial to patient care, and subtyping of malignant mesotheliomas is important for selection of treatment options and estimating prognosis. These issues can present problems using routine morphology, and a variety of (sometimes controversial) markers have been proposed as aids.
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
Stories abound of a “cancer-curing” tea from the forests of Canada. Herbal blends claim to “attack cancer at the DNA level.” For many years, mesothelioma patients have turned to alternative medicines like these as treatment options for the rare asbestos-related cancer. Sometimes these options are a last resort, after traditional treatments fail. They may be used in conjunction with standard treatment (complementary medicine) or on their own as the main approach. But the U.S. Food and Drug Administration (FDA) recently issued warning letters to companies that manufacture or market products claimin...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: Alternative medicine Asparagus Extract BioStar Technology International Budwig Protocol cancer supplements cannabis oil cancer CellAssure Centers for Disease Control and Prevention Chelated Boron Circulatory Detox & Support Syrup compl Source Type: news
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