This Year ’s Flu Shot Was Far More Effective Than Last Year’s. Here’s Why

The 2018-2019 flu season has been a relatively mild one — and a pretty effective flu shot is part of the reason why. Mid-season estimates suggest that the flu shot has reduced the risk of illness by around 47% in vaccinated people, according to a report from the Centers for Disease Control and Prevention (CDC) released Thursday. During the severe 2017-2018 flu season, vaccine efficacy was estimated at just 36%. The difference is partly because the dominant influenza virus last year, H3N2, is known to cause more serious illnesses and to be less responsive to vaccination than other strains. This year, H1N1 — which is more easily targeted by the flu shot — has been circulating most widely, leading to less-severe and fewer illnesses overall. The CDC estimates that the flu shot reduced the risk of H1N1 infection by about 46% among adults, and about 62% among children ages six months to 17 years old. The shot’s effectiveness — and higher-than-average early-season vaccination rates — have contributed to a comparably mild flu season this year. But activity began picking up in January and is expected to continue for “several more weeks,” the CDC says. As of early February, about 4.3% of outpatient medical visits in the U.S. were due to influenza-like illness, according to the CDC. At this time during the 2017-2018 season, 7.7% of outpatient medical visits were caused by the flu. Flu- and pneumonia-related deaths have also been less comm...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime public health Source Type: news

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Conclusions: Human challenge studies and systems biology approaches are important tools that should be used in concert to advance our understanding of influenza infection and provide targets for novel therapeutics and immunizations. Introduction Although influenza virus was recognized as an important pathogen over a century ago, influenza continues to cause a significant burden of disease. In the United States alone, it's estimated that in the 2017–2018 season there were 959,000 hospitalizations related to influenza illness, and 79,400 deaths (CDC, 2018). Worldwide, WHO estimates that annual influenza...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
(CNN) — Flu activity remains high across the nation, and there’s a second wave of severe infections striking some states. There were as many as 26.3 million flu illnesses, 12.4 million medical visits and 347,000 flu hospitalizations between October 1 and March 2, according to the weekly flu report released Friday by the US Centers for Disease Control and Prevention. “We’re still having flu. And we’re still seeing a steady stream of patients who are being admitted to hospital with influenza,” said Dr. William Schaffner, medical director of the National Foundation for Infectious Diseases. ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Flu Source Type: news
Abstract CDC collects, compiles, and analyzes data on influenza activity and viruses in the United States. During September 30, 2018-February 2, 2019,* influenza activity† in the United States was low during October and November, increased in late December, and remained elevated through early February. As of February 2, 2019, this has been a low-severity influenza season (1), with a lower percentage of outpatient visits for influenza-like illness (ILI), lower rates of hospitalization, and fewer deaths attributed to pneumonia and influenza, compared with recent seasons. Influenza-associated hospitalization r...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
(CNN) — Most US adults have not gotten a flu shot this season, according to a new survey from NORC, a research organization at the University of Chicago. As of mid-November, only 43% of surveyed people 18 or older said they had gotten vaccinated against the flu, according to NORC, which has conducted the National Immunization Survey for the US Centers for Disease Control and Prevention since 2005. Another 14% who remain unvaccinated claim that they will get the shot, the survey indicates. Even if they do as they intend, that leaves considerably more than a third of adults (41%) who have not — and will not &mdas...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Flu Flu Shot Local TV Source Type: news
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Source: Influenza and Other Respiratory Viruses - Category: Virology Authors: Tags: Short Article Source Type: research
The Objective: To assess the seasonal incidence rate (IR) and mortality rate (MR) because of acute respiratory viral infections (ARVI) and pneumonia (P) in the population of Moscow.The Methods: We used the data on IR and MR of the population because of infectious and parasitic diseases (IPD) (A00-V99 ICD-10), ARVI (J00-02.8-9; J03-J06; J20-J22 ICD-10), P (J12-J16, J18 MCD-10) of the official statistical forms 1, 2, 5, medical death certificates (MDC) of patients from hospitals, microbiology assays nasopharyngeal swabs identifying RNA of influenza virus A(H1N1)09, A(H3N2) and B; bacteriological examinations of sputum.Result...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
AbstractWe evaluated the anti-influenza-virus effects ofMelia components and discuss the utility of these components. The effects of leaf components ofMelia azedarach L. on viruses were examined, and plaque inhibition tests were performed. Thein vivo efficacy ofM. azedarach L. was tested in a mouse model. Leaf components ofMelia azedarach L. markedly inhibited the growth of various influenza viruses. In an initial screening, multiplication and haemagglutination (HA) activities of H1N1, H3N2, H5, and B influenza viruses were inactivated by the liquid extract of leaves ofM. azedarach L. (MLE). Furthermore, plaque inhibition ...
Source: Archives of Virology - Category: Virology Source Type: research
Conclusions: Often manifested as lower respiratory tract infection, influenza may cause epidemics with increased mortality rate. Influenza should be suspected when interstitial pattern was seen on radiological images. H1N1 cases course worse. Since the prognosis is better in vaccinated patients, seasonal influenza vaccination among the community needs to be elevated. In addition, protective measures like vaccination should be taken in pregnancy to avoid preterm delivery or abortion. PMID: 30246658 [PubMed - in process]
Source: Tuberkuloz ve Toraks - Category: Respiratory Medicine Authors: Tags: Tuberk Toraks Source Type: research
By Susan Scutti, CNN (CNN) — Flu has been shown the door in the United States. Illness activity peaked and began to decline during the eighth week of the year, the US Centers for Disease Control and Prevention’s weekly surveillance report indicated Friday. Just 5% of people who visited their doctors did so while complaining of flu-like illness, down from 6.4% the previous week. Caused by viruses, flu is a contagious respiratory illness with mild to severe symptoms that can sometimes lead to death. “We have definitely peaked,” CDC spokeswoman Kristen Nordlund said, quickly adding, “that doesn&r...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Flu Source Type: news
Early estimates suggest the flu shot only worked about a third of the time this year. Between Nov. 2 and Feb. 3, total vaccine effectiveness was estimated at 36%, according to a report released Thursday by the CDC. When broken down by strain, however, efficacy varied widely. H3N2, the dominant strain circulating this flu season, is notoriously more virulent and less receptive to vaccination than other types of influenza. True to form, vaccine effectiveness against this strain was low this year — approximately 25%, according to the CDC report. (That’s actually better than experts originally feared, based on tren...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime onetime public health Source Type: news
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