Radiation induced DNA damage response and resistance in colorectal cancer stem-like cells.

CONCLUSION: This study highlighted the presence of CSC phenotype in clonospheres having increased DNA repair capacity. Differential expression of developmental marker, CSC markers and telomeric components between parental and clonospheres may contribute in radio-resistance property of CSCs. PMID: 30753097 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research