The reduction of apnea –hypopnea duration ameliorates endothelial dysfunction, vascular inflammation, and systemic hypertension in a rat model of obstructive sleep apnea

ConclusionsLonger apnea –hypopnea duration is related to more systemic inflammatory and endothelial dysfunction, and hypertension and cardiac remodeling. These can be reversed after a period of recovery, which indicates that time parameters for assessing OSA, such as apnea–hypopnea duration, should be considered instea d of apnea–hypopnea index only.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research