Investigation of the refractive index decrement of 3D printing materials for manufacturing breast phantoms for phase contrast imaging.

Investigation of the refractive index decrement of 3D printing materials for manufacturing breast phantoms for phase contrast imaging.
Phys Med Biol. 2019 Feb 12;:
Authors: Esposito G, Mettivier G, Bliznakova K, Bliznakov Z, Bosmans H, Bravin A, Buliev I, Di Lillo F, Ivanov D, Minutillo M, Sarno A, Vignero J, Russo P
Abstract
3D breast modelling for 2D and 3D breast X-ray imaging would benefit from the availability of digital and physical phantoms that reproduce accurately the complexity of the breast anatomy. While a number of groups have produced digital phantoms with increasing level of complexity, physical phantoms reproducing that software approach have been scarcely developed. One possibility is offered by 3D printing technology. This implies the assessment of the energy dependent absorption index β of 3D printing materials for absorption based imaging, as well as the assessment of the refractive index decrement, δ, of the material, for phase contrast imaging studies, at the energies of interest for breast imaging. In this work we set-up a procedure and performed a series of measurements (at 30, 45 and 60 keV, at the European Synchrotron Radiation Facility) for assessing the relative value of δ with respect to that of breast tissues, for twelve 3D printing materials. The method included propagation based phase contrast 2D imaging and retrieval of the estimated phase shift map, using the Paganin algorithm. Breast glandular, a...

Source: Physics in Medicine and Biology - February 12, 2019 Category: Physics Authors: Esposito G, Mettivier G, Bliznakova K, Bliznakov Z, Bosmans H, Bravin A, Buliev I, Di Lillo F, Ivanov D, Minutillo M, Sarno A, Vignero J, Russo P Tags: Phys Med Biol Source Type: research