Sinks by Toilets in ICU Patient Rooms Harbor Harmful Bacteria

WEDNESDAY, Feb. 13, 2019 -- Sinks next to toilets in hospital patient rooms may be reservoirs for Klebsiella pneumonia carbapenemase (KPC), according to a brief report published in the January issue of the American Journal of Infection...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Authors: Sarda C, Fazal F, Rello J Abstract Introduction: Treatment of ventilator-associated pneumonia (VAP) is a major challenge. The increase in multi-drug resistant bacteria has not been accompanied by the validation of new drugs, or by any new antimicrobial strategies to exploit the available agents. VAP due to Gram-negative bacteria has increased mortality, both due to the resistant pathogens themselves and due to inappropriate treatment. Local epidemiology, patients' characteristics and clinical responses provide the most important information for therapeutic decision-making. Moreover, data on VAP therapy due...
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
Publication date: Available online 18 June 2019Source: Respiratory Medicine Case ReportsAuthor(s): Ryota Shintani, Tsuneyuki Oda, Takashi Niwa, Akimasa Sekine, Eri Hagiwara, Koji Okudela, Tamiko Takemura, Takashi OguraAbstractA 53-year-old Japanese female was admitted to our hospital with 3-week history of cough and worsening dyspnea. Chest computed tomography revealed unilateral focal consolidation in the right lower lobe. She underwent transbronchial lung cryobiopsy (TBLC) and histology showed acute fibrinous and organizing pneumonia (AFOP). High-dose methylprednisolone treatment improved her respiratory condition and ra...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
This study aims to investigate the diagnostic and prognostic values of miRNAs in sepsis secondary to pneumonia. MiR-223-3p could be utilized to predict sepsis secondary to pneumonia.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
We investigated the risk and prognostic factors of pure viral sepsis in adult patients with community-acquired pneumonia (CAP), using the Sepsis-3 definition. Pure viral sepsis was found in 3% of all patients admitted to the emergency department with a diagnosis of CAP (138 out of 4,028), 19% of all CAP patients admitted to the intensive care unit (ICU) (138 out of 722) and 61% of all patients with a diagnosis of viral CAP (138 out of 225). Our data indicate that males and patients aged ≥65 years are at increased risk of viral sepsis
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Authors: Christie DB, Nowack T, Drahos A, Ashley DW Abstract Geriatric trauma has become an increasingly recognized management concern for trauma centers, and hospitals alike, on a national scale. The population of the United States is aging, as life expectancy rates have demonstrated a steady climb to an average of 78.8 years of expected life. With pervasive efforts of medical screening, prevention and chronic medical condition management, more elderly people will lead more active lifestyles and will be more predisposed to injury. As best practice guidelines specific for the geriatric trauma population have yet to...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Publication date: September 2019Source: Biomedicine &Pharmacotherapy, Volume 117Author(s): Guorong Zhang, Chunhong Jiang, Ning Xie, Yang Xu, Li Liu, Nan LiuAbstractKlebsiella pneumoniae is a primary cause of community-acquired and nosocomial respiratory infections, and K. pneumoniae resistance to the current treatment approach with carbapenem is worsening. Andrographolide is a natural diterpenoid from Andrographis paniculata that was shown to exert anti-inflammatory activity. We herein show that pretreatment with a water-soluble andrographolide sulfonate significantly attenuate lung injury and infiltration of inflammat...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
CONCLUSIONS: DM patients with poor glucose control are more susceptible to MRSA infection. They suffer from higher antimicrobial resistance, a higher co-infection rate, and much severer pneumonia than non-DM. MRSA itself is an independent risk factor for mortality in all patients. PMID: 31205100 [PubMed - in process]
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
CONCLUSIONS: CPET may greatly facilitate the diagnosis of unexplained dyspnoea. More than 50% of the dyspnoea cases examined here were due to deconditioning or hyperventilation syndrome and would benefit from a simple pulmonary rehabilitation program. PMID: 31204232 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
CONCLUSION: Rarely, emphysematous bullae resolve following infections. Further studies of the mechanisms involved in these natural regressions may be of interest in the development of new therapeutics. PMID: 31202604 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
CONCLUSION: The diagnosis of hypersensitivity pneumonitis should be considered in similar cases. Treatment is based mainly on removing exposure to the causative antigen. PMID: 31202600 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
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