Heart failure survival rates have barely improved in TWO decades

The terminal condition – which is often mistaken for asthma or mere old age – currently affects more than 920,000 people in the UK. The chances of dying from heart failure have hardly changed since 2000.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Abstract Transported desert dust particles (TDDP) are soil particles suspended in the air. Being spread all over the globe by the winds, TDDP affect animals, including humans, plants and other organisms not only in the areas of their emission. In humans, TDDP are responsible for diseases of the respiratory (e.g. asthma) and circulatory (e.g. heart failure) systems and they also act directly on the epithelium and its mucus layer after deposition in the mouth and respiratory system. The aim of the study was to determine the influence of TDDP on the rheology of mucus and saliva, and thus on their functioning. The art...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Tags: Environ Sci Pollut Res Int Source Type: research
Conclusions: In special circumstances, ALS guidelines require modification and special attention for causes, environment, and patient particularities, with specific therapeutic intervention concomitant with standard ALS.
Source: American Journal of Therapeutics - Category: Drugs & Pharmacology Tags: Systematic Reviews Source Type: research
Publication date: Available online 21 February 2019Source: The Lancet Global HealthAuthor(s): Peter C Rockers, Richard O Laing, Paul G Ashigbie, Monica A Onyango, Carol K Mukiira, Veronika J WirtzSummaryBackgroundNovartis Access is a Novartis programme that offers a portfolio of non-communicable disease medicines at a wholesale price of US$1 per treatment per month in low-income and middle-income countries. We evaluated the effect of Novartis Access in Kenya, the first country to receive the programme.MethodsWe did a cluster-randomised controlled trial in eight counties in Kenya. Counties (clusters) were randomly assigned ...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Vapotherm said today that it launched its next-gen Precision Flow Hi-VNI system intended to relieve respiratory stress in spontaneously breathing patients. The Exeter, N.H.-based company touted that the next-gen device features improvements to both its software and hardware intended to improve reliability. The Precision Flow Hi-VNI system is designed to deliver maskless noninvasive ventilation to patients who are spontaneously breathing to relieve respiratory distress including hypercapnia, hypoxemia and dyspnea, Vapotherm said. The company’s Precision Flow devices are intended to provide high-velocity heated, humidi...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Respiratory Vapotherm Source Type: news
ConclusionsPatients suffering from OSAS have very high prevalence of comorbidities indicating a great burden on the healthcare system. Despite this fact, over 50% of the patients studied did not receive any treatment. Charities were the main portal fortreatment.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
CONCLUSIONS: Patients suffering from OSAS have very high prevalence of comorbidities indicating a great burden on the healthcare system. Despite this fact, over 50% of the patients studied did not receive any treatment. Charities were the main portal fortreatment. PMID: 30685854 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Tags: Sleep Breath Source Type: research
Discovery of β-arrestin-biased β2-adrenoceptor agonists from 2-amino-2-phenylethanol derivatives. Acta Pharmacol Sin. 2019 Jan 14;: Authors: Woo AY, Ge XY, Pan L, Xing G, Mo YM, Xing RJ, Li XR, Zhang YY, Wainer IW, Cheng MS, Xiao RP Abstract β-Arrestins are a small family of proteins important for signal transduction at G protein-coupled receptors (GPCRs). β-Arrestins are involved in the desensitization of GPCRs. Recently, biased ligands possessing different efficacies in activating the G protein- versus the β-arrestin-dependent signals downstream of a single GPCR have emerged...
Source: Acta Pharmacologica Sinica - Category: Drugs & Pharmacology Authors: Tags: Acta Pharmacol Sin Source Type: research
In a blog post last week, I shared an excerpt from the new book that Paul Cerrato and I just completed,The Transformative Power of Mobile Medicine. Here is a second excerpt from Chapter 3,  “Exploring the Strengths and Weaknesses of Mobile Health Apps.”Even patients who are fully engaged in their own care still need access to medical apps they can trust. The IQVIA Institute for Human Data Science has performed a detailed analysis of the clinical evidence supporting mobile health apps, rating their maturity and relative quality. Its rating scale places a single observational study near the bottom of th...
Source: Life as a Healthcare CIO - Category: Information Technology Source Type: blogs
Conclusion: Rib raising was shown to be well tolerated by the majority of the patients in the study population. PMID: 30556829 [PubMed - as supplied by publisher]
Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research
‚ÄčI recently met with a group from our children's hospital to standardize the hospital management of bronchiolitis according to the latest American Academy of Pediatrics guidelines. (Pediatrics 2014;134[5]:e1474; http://bit.ly/2QIGbMX.) Unfortunately, these guidelines seem to cause confusion for experienced and inexperienced emergency physicians alike.This confusion comes from the guidelines raising unaddressed issues and new questions, most importantly not tackling important aspects of frontline clinical practice. These guidelines were developed with the best evidence currently available, and their application mostly cau...
Source: M2E Too! Mellick's Multimedia EduBlog - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
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