Bugs Vs. Superbugs: Insects Offer Promise In Fight Against Antibiotic Resistance

Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news

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Study Design. A retrospective database analysis among Medicare beneficiaries Objective. The aim of this study was to determine the effect of chronic steroid use and chronic methicillin-resistant Staphylococcus aureus (MRSA) infection on rates of surgical site infection (SSI) and mortality in patients 65 years of age and older who were treated with lumbar spine fusion. Summary of Background Data. Systemic immunosuppression and infection focus elsewhere in the body are considered risk factors for SSI. Chronic steroid use and previous MRSA infection have been associated with an increased risk of SSI in some surgical p...
Source: Spine - Category: Orthopaedics Tags: CLINICAL CASE SERIES Source Type: research
(Frontiers) Researchers have taken another small step towards deep space exploration, by testing a new silver- and ruthenium-based antimicrobial coating aboard the International Space Station (ISS). Published in Frontiers in Microbiology, their study shows that the AGXX ® dramatically reduced the number of bacteria on contamination-prone surfaces -- and could help protect future astronauts beyond the moon and Mars.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Lydia-Yasmin Sobisch, Katja Marie Rogowski, Jonathan Fuchs, Wilhelm Schmieder, Ankita Vaishampayan, Patricia Oles, Natalia Novikova, Elisabeth Grohmann
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Anand Manoharan, Ranjith JayaramanIndian Journal of Medical Microbiology 2018 36(4):465-474Streptococcus pneumoniae continues to take a heavy toll on childhood mortality and morbidity across the developing world. An estimated 10.6 million invasive pneumococcal diseases (IPDs) occur every year, with nearly 1 million deaths in children under 5 years of age. Introduction of vaccines in the childhood immunisation programme in developed world has brought down the incidence of the disease considerably. However, childhood immunocompromising illnesses including HIV have increased the risk of IPD several folds. There is also a grow...
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research
Conclusions: Carriage of MDR strains with a potential to express multidrug resistance poses a threat of dissemination in the community. Awareness for restricted use of antibiotics and proper sanitation can contain the spread of resistant bacteria.
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research
Conclusion: This study provided evidence that ethanol extract of A. oliveriava and A. aucheri can inhibit the biofilm formation of S. aureus. As a traditional Iranian medicine, A. oliveriava and A. aucheri extracts have a potential antibiofilm formation against MRSA strains. PMID: 30873270 [PubMed]
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
Conclusion: Due to the significant antibacterial potency of bacteria-treated larvae secretions, the secretions can be a suitable candidate as a drug against antibiotic resistant bacteria, but additional tests are required. Since the antimicrobial peptides of insects have not yet produced any resistance in human pathogenic bacteria, they can be considered as a promising strategy for dealing with resistant infections. PMID: 30873269 [PubMed]
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
This study included bacterial cultures, antibiotic sensitivities and resistance pattern in breast abscesses. Results: 268 patients were included in the study. 143 (53.4%) were Lactational abscesses and 125 (46.6%) were non-Lactational abscesses. 169 (63.0%) harbored S. aureus in which 86 (50.8%) were MRSA. MRSA was the predominant organism in the Lactational group while non-Lactational group had no growth or other organisms in culture in this study. Other growing organisms were Klebsiella pneumoniae, Bacteroides, Pseudomonas, Streptococcus species and Mycobacterium tuberculosis. On comparative analysis, MRSA showed sta...
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
Publication date: Available online 15 March 2019Source: Microbial PathogenesisAuthor(s): Yiguo Chen, Shanshan Lu, Yong Zhang, Jinmei Yu, Linqiang Deng, Hui Chen, Yujuan Zhang, Nanjin Zhou, Keng Yuan, Lizhi Yu, Zhanghua Xiong, Xiaomei Gui, Yanrong Yu, Weiping MinAbstractA proliferation of studies have demonstrated that the toll-like receptor 2 (TLR2) pathway affects the chemotaxis, phagocytosis, and cytokine release of neutrophils when pathogens invade. Our previous studies have demonstrated that pretreatment with high doses of Pam3CSK4 (>25 μg/ml) improves the antimicrobial activity of neutrophils, however, short-l...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionsThe current practice for removing a patient from contact precautions for MRSA is insufficient. The number of negative nasal swabs required should be increased from 2 to 3 and a decolonization protocol should be implemented.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
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