Medical News Today: How sleep can boost your body's immune response

New research pinpoints the mechanism through which sleep helps boost the activity of immune cells, thereby enhancing the body's immune response.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

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Abstract Neuropsychiatric adverse events (NPAEs) observed with the integrase strand transfer inhibitor (INSTI) dolutegravir (DTG) are usually mild to moderate. The most prevalent symptoms are insomnia and sleep disorders, but the spectrum also includes dizziness, anxiety, depression, headache, paraesthesia, muscle-skeletal pain, poor concentration, and slow thinking. In recent cohort studies involving>6400 patients in different countries, discontinuation rates due to NPAEs were observed in around 3.5% (range, 1.4-7.2%) of subjects treated with DTG. These rates have been higher than those seen in randomized clin...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
This study examined: (1) some of the psychometric properties of the Insomnia Sev...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Conclusions: MBTs can be effective in treating insomnia and improving sleep quality for healthy individuals and clinical patients. More high-quality and well-controlled RCTs are needed to make a better conclusion in further study. PMID: 30894878 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Abstract Fatal Familial Insomnia (FFI) is a hereditary prion disease caused by a mutation at codon 178 of the prion-protein gene leading to a D178N substitution in the protein determining severe and selective atrophy of mediodorsal and anteroventral thalamic nuclei. FFI is characterized by physiological sleep loss, which polygraphically appears to be a slow wave sleep loss, autonomic and motor hyperactivation with peculiar episodes of oneiric stupor. Alteration of autonomic functions is a great burden for FFI patients consisting in sympathetic overactivation, dysregulation of its physiological responses and disrup...
Source: Autonomic Neuroscience - Category: Neuroscience Authors: Tags: Auton Neurosci Source Type: research
Abstract Cardiovascular disease (CVD) represents the first cause of death globally. The nighttime is generally a period of relative protection from CVD events such as myocardial infarction, sudden cardiac death, and stroke, at least compared to the early morning period. The nighttime also generally entails lower values of arterial blood pressure (ABP) and heart rate (HR) and higher cardiac parasympathetic modulation. These day-night cardiovascular rhythms are ultimately driven by circadian molecular oscillators in the hypothalamic suprachiasmatic nucleus and in peripheral cells, including those in the heart, blood...
Source: Autonomic Neuroscience - Category: Neuroscience Authors: Tags: Auton Neurosci Source Type: research
Conditions:   Sleep Fragmentation;   Poor Quality Sleep;   Nocturia;   Nocturnal Enuresis Interventions:   Behavioral: Brief behavioral treatment of insomnia (BBTI);   Behavioral: Information-only control (IC) Sponsors:   University of Pittsburgh;   National Institute on Aging (NIA) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
(University of Oxford) Oxford University researchers have discovered a brain process common to sleep and aging in research that could pave the way for new treatments for insomnia.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
IK Abstract The purpose was to investigate the psychometric properties of the Insomnia Catastrophizing Scale (ICS) including factorial validity and internal consistency as well as discriminative and convergent validity. Associations with sleep parameters and daytime impairment are also examined. Drawn from a randomly selected sample of the general population, 1615 participants completed a survey on insomnia-related nighttime and daytime symptoms, health outcomes and psychological processes, including the ICS. A one-factor solution was supported for both the nighttime catastrophizing (11 items) and daytime catastr...
Source: Cognitive Behaviour Therapy - Category: Psychiatry & Psychology Authors: Tags: Cogn Behav Ther Source Type: research
A new study by Oxford University reveals the 'internal stress' that ages our cells and triggers disease also activates neurones that control sleep in fruit flies, with human cells being similar.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
New research finds an autoreactive type of immune cell related to narcolepsy, adding to the mounting body of evidence that the condition is autoimmune.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news
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