Analysis of amino acids in blood by combining zeolitic imidazolate framework-8-based solid phase extraction and capillary electrophoresis
Publication date: Available online 13 February 2019Source: Journal of Pharmaceutical and Biomedical AnalysisAuthor(s): Zhenqun Li, Jia Wu, Li JiaAbstractDetection of amino acids (AAs) in blood is helpful to diagnose some diseases. In this work, a method is developed for determination of trace amounts of AAs in bovine blood by combining solid phase extraction (SPE) and capillary electrophoresis (CE). Zeolitic imidazolate framework-8 (ZIF-8) nanoparticles are prepared and used as adsorbents to simultaneously extract three AAs (tryptophan, tyrosine, phenylalanine). Under the optimum extraction conditions, the extraction efficiencies of ZIF-8 for AAs are 95.1% (tryptophan), 91.1% (tyrosine), and 90.1% (phenylalanine), respectively. Interestingly, ZIF-8 demonstrates good extraction ability for AAs in high concentration of acetonitrile (ACN) aqueous solutions. Thus, they can be directly used to extract AAs from the deproteinized blood sample using ACN. An α-cyclodextrin-mediated cation selective exhaustive injection-sweeping CE method is developed for analysis of the extracted AAs. The detection limits for AAs range from 0.13 to 0.37 μg mL−1 using the SPE/CE method. Standard addition method is used to evaluate the feasibility of the method in bovine blood samples. The standard addition curves demonstrate good linearity with determination coefficient> 0.9912.
Houston-based Christus Foundation for Healthcare received a $3 million donation to finish construction on its East End clinic. Christus Foundation for Healthcare received the gift from Irving, Texas-based Catholic nonprofit health system Christus Health, according to a Nov. 11 press release. The funds will go toward completing construction on the new Christus St. Mary's Clinic building on the St. Austin Center campus at 2 002 S. Wayside Drive. The clinic is nearly doubling in size — from 4,500…
Authors: Nagy P, Molnar B, Nemes B, Schupbach P, Windisch P Abstract The aim of this case series was the histologic evaluation of guided tissue regeneration utilizing deproteinized bovine bone mineral (DBBM) when regenerative surgery was combined with (test) or without (control) early orthodontic tooth movement. Core biopsy samples were harvested from previously defected sites after 9 months. The histologic section showed integration of DBBM particles in newly formed bone in the apical and middle thirds of the defect, while in the coronal part, graft materials were mainly embedded in connective tissues in the contr...
Authors: Al Balbeesi HO, Al Kawari HM, Al Tamimi AS, Al Mubarak I, Al Ibrahim KI, Divakar DD Abstract In the present study, the authors evaluated the association of canine impaction with different skeletal discrepancies in two planes of space (sagittal and vertical). Cephalometric and orthopantomographic radiographic images of 45 patients with one or more impacted canines were used in this retrospective study. Five radiographic morphologic parameters-ANB angle, canine angulation, angle between the Frankfort horizontal plane and the mandibular plane (FH-MP), Wits appraisal analysis, and axial inclination of the maxi...
[Cameroon Tribune] A genomic company known as 54gene is building the first pan-African Biobank that will target many diseases.
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This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Cynthia Richard, Armaghan Fakhfouri, Melanie Colditz, Friedrich Striggow, Romy Kronstein-Wiedemann, Torsten Tonn, Mariana Medina-S ánchez, Oliver G. Schmidt, Thomas Gemming, Andreas Winkler SAW-based acoustofluidic blood platelet separation at 2.7 × 104 cells per s throughput in a comprehensively analysed and numerical simulated, wafer-scale manufactured device. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
New J. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9NJ04598H, LetterXiao Li, Xiao-Li Hu, Xinlong Wang, Qing-Qing Pan, Lei Liu, Zhong-Min Su The production of hydrogen via electrochemical water splitting combind with fuel cells is a promising way to realize sustainable energy system. Herein, we report a simple one-step, scalable glucose-blowing method... The content of this RSS Feed (c) The Royal Society of Chemistry