Thioflavin T Specifically Brightening “Guanine Island” in Duplex-DNA: A Novel Fluorescent Probe for Single-Nucleotide Mutation

Analyst, 2019, Accepted Manuscript DOI: 10.1039/C8AN02430H, PaperXiaohong Li, Wei Zhou, Ze Yu, Ge Ma, Tian Jin, Yunchao Li, Louzhen Fan Here, we found that Thioflavin T (ThT) could specifically bind with a G-GGG unit (named as “Guanine Island”) in double stranded DNA (ds-DNA). Through stacking with G base via hydrogen... The content of this RSS Feed (c) The Royal Society of Chemistry
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