Ketamine-like depression treatment on track for FDA approval

A ketamine-like drug for treatment-resistant depression was backed by a US Food and Drug Administration advisory committee on Tuesday. If it is then approved by the FDA, the drug -- called esketamine -- may provide a new option for patients with major depressive disorder who have tried at least two other antidepressants without success.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

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BACKGROUND AND OBJECTIVES: Late-life depression is a major societal concern, but older adults' attitudes toward its treatment remain complex. We aimed to explore older adults' views regarding depression and its treatment. RESEARCH DESIGN AND METHODS: We un...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
We aimed at clarifying the strength and consistency of the association between cannabis use disorder and suicide attempts in bipolar disorder. We conducted a systematic review and meta-analysis of observational studies providing cross-sectional and longitu...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
This study examined competing models considering each problem domain individually as a driving mechanism for the other problems to better understand etiology and inform prevention efforts. Ge...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Introduction. Over 1 million mild traumatic brain injury (mTBI) cases are reported annually worldwide and may result in cognitive, physical, and emotional deterioration; depression; anxiety; and sleep problems. However, studies on long-term mTBI eff...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news
Sleep disturbance and respiratory sinus arrhythmia (RSA) are well-known to be independently associated with depression. Yet, it remains unclear how sleep disturbance and impaired physiological regulation (indexed by RSA) may synergistically contribute to d...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news
Individuals diagnosed with attention-deficit/hyperactivity disorder (ADHD) across the life span are at significantly increased risk for a wide range of adverse outcomes, including substance use, obesity, and suicidal behavior. Risky driving, measured in...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Although there has been an increase in public health campaigns and initiatives aimed at preventing suicidal behaviors, suicide rates in Canada appear to be increasing particularly among young adults. Yet, few studies in Canada have examined the effect of s...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
OBJECTIVE To explore the dimensionality of the Beck Depression Inventory (BDI) among Colombian college students. Methods A validation study was designed, involving the participation of a sample of 786 health science students (medicine, nursing, a...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
PURPOSE To examine the cross-lagged associations between delinquency (nonviolent and violent), depression and anxiety symptoms in adolescence and to test the moderating effect of sex and family socioeconomic status (SES). Methods Participants (n=1,515)...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
OBJECTIVEsPrior studies have documented that mobile phone addiction is linked to anxiety and depression. However, the underlying processes that might moderate these associations remain unclear. The present research tested whether mindfulness moderated the ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
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