Nasal spray made from KETAMINE wins FDA panel's backing for treating depression

In recent years, the party drug ketamine, or 'special K' has shown promise for treating tough cases of depression. A key FDA panel has given its support to Johnson &Johnson's ketamine-derived spray.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Publication date: August 2019Source: Current Opinion in Behavioral Sciences, Volume 28Author(s): Annelise Madison, Janice K Kiecolt-GlaserHumans and their gut bacteria have evolved multiple ways to communicate with and regulate one another. Psychological stress and depression can promote consumption of highly palatable foods, influencing which gut bacteria thrive. Additionally, stress and depression can reshape the gut bacteria’s composition through stress hormones, inflammation, and autonomic alterations. In turn, the gut bacteria release metabolites, toxins, and neurohormones that can alter eating behavior and mood...
Source: Current Opinion in Behavioral Sciences - Category: Psychiatry & Psychology Source Type: research
CONCLUSION: Our results suggest that reappraisal represents a protective factor against the deleterious effects of suppression on stress responsivity. This study underlines the importance of investigating emotion regulation strategies as a means to understand individual differences in vulnerability to stress-related psychopathologies such as anxiety and depression. PMID: 30908108 [PubMed - in process]
Source: Anxiety, Stress, and Coping - Category: Psychiatry & Psychology Authors: Tags: Anxiety Stress Coping Source Type: research
Source: BMJ News - Category: General Medicine Source Type: research
Publication date: Available online 25 March 2019Source: Journal of the Formosan Medical AssociationAuthor(s): Hung-Da Chen, Ming-Jong Bair, Wei-Chuan Chang, Ching-Sheng Hsu, Ming-Wun Wong, Jui-Sheng Hung, Tso-Tsai Liu, Chih-Hsun Yi, Wei-Yi Lei, Chien-Lin ChenBackgroundIrritable bowel syndrome (IBS) and functional constipation (FC) are highly prevalent in the general population and have significant symptom overlap, while the clinical associations and psychological links between IBS and FC remains poorly understood. We aimed to compare the clinical, metabolic and psychological factors between patients with FC patients and c...
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
ConclusionsOur in vitro and in vivo results indicate that the neuroprotective effect of ZSXPT against autophagy-induced damage and apoptosis occurs mainly by blocking the mTOR pathway in Cort-induced PC12 cells and in FD rats. Taken together, these data provide reliable experimental evidence and explain the molecular mechanism by which ZSXPT ameliorates FD.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Terminally ill adults in New Jersey will soon be able to ask for medical help to end their lives.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: Precipitation due to suicide attempt causes 2% of spinal cord injuries, with depression and psychotic disorders being the most prevalent psychiatric disorders. After the rehabilitation period, this population requires special attention from the mental health teams since they combine risk factors to commit suicide such as the history of previous attempts and the presence of a chronic disabling condition. PMID: 30906978 [PubMed - in process]
Source: Revista de Neurologia - Category: Neurology Authors: Tags: Rev Neurol Source Type: research
CONCLUSIONS: The results support the efficacy, feasibility and acceptability of the intervention for mild neurocognitive disorder and justify a randomized controlled trial of the program with a larger sample. PMID: 30906977 [PubMed - in process]
Source: Revista de Neurologia - Category: Neurology Authors: Tags: Rev Neurol Source Type: research
Tomoe Sakashita, Hirofumi Oyama
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Authors: Pichon J, Chouaid C, Marc E, Voiriot G Abstract Airborne isolation is the main confinement measure used to limit human-to-human transmission of tuberculosis. If implemented early, precisely as soon as the patient is clinically diagnosed with tuberculosis, this measure will protect the population, particularly the health workers who are exposed. A patient suspected of being infected with tuberculosis can create a difficult situation if microbiological examination of his respiratory secretions is negative. This is a complex laboratory technique and sensitivity varies from one test to another. Thus, a false n...
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
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