Nociceptin/orphanin FQ modulates energy homeostasis through inhibition of neurotransmission at VMN SF-1/ARC POMC synapses in a sex- and diet-dependent manner

ConclusionThese findings show that males are more responsive to the pleiotropic actions of N/OFQ at anorexigenic VMN SF-1/ARC POMC synapses, and this responsiveness can be further enhanced under conditions of diet-induced obesity/insulin resistance.
Source: Biology of Sex Differences - Category: Biology Source Type: research

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Conclusions Patients are not adequately ready to change their health-related behaviors. Higher cardiovascular risk predicts higher readiness to change health behaviors.
Source: Journal of Nursing Research - Category: Nursing Tags: ORIGINAL ARTICLES Source Type: research
Conclusions: IENFD measurement in postmortem skin is feasible and may be used to study the epidemiology of SFN.
Source: Journal of Clinical Neuromuscular Disease - Category: Neurology Tags: Original Article Source Type: research
Conditions:   Breast Cancer;   Morbid Obesity;   Bariatric Surgery Candidate Intervention:   Procedure: Bariatric surgery Sponsor:   The Cleveland Clinic Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Cancer;   Cancer Survivors;   Chemotherapy-induced Peripheral Neuropathy;   Obesity Intervention:   Behavioral: Whole body vibration (WBV) plus low intensity exercise Sponsors:   OHSU Knight Cancer Institute;   National Cancer Institute (NCI);   Oregon Health and Science University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Morbid Obesity Intervention:   Sponsors:   National and Kapodistrian University of Athens;   Beth Israel Deaconess Medical Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 20 November 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Hema S. Gopalan, Intazaamul-Haq, Shamshad Ahmad, Ashok Gaur, Anoop MisraAbstractDiabetes is on the rise in India and recently shown to be increasing in the urban underprivileged. Lack of awareness of the disease, its complications, combined with lack of financial resources among the underprivileged, often results in late detection and more complications in them. To combat this, healthcare delivered at the doorstep through the use of a customised mobile medical van is a potentially attractive...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 19 November 2019Source: Journal of EthnopharmacologyAuthor(s): Lujie Fan, Ying Peng, Dan Wu, Jianhong Hu, Xin'e Shi, Gongshe Yang, Xiao LiAbstractEthnopharmacological relevanceMulberry leaves are the dry leaves of Morus nigra L. trees, which are widely cultivated in central and southern China. Mulberry has a long history of medicinal use, such as anti-stress, lowering blood glucose and anti-obesity.Aim of the studyExplore the effects of mulberry leaves on fat deposition as well as the underlying mechanisms.Materials and methodsTotal of 48 fattening pigs weighing about 70 kg were randoml...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionAs a result of this equivocal outcome within the systematic review, body mass index and dental caries present as a complex association. Further long-term studies are required to translate the findings into clinical practice.
Source: The Saudi Dental Journal - Category: Dentistry Source Type: research
Some of the most common symptoms experienced by cancer patients are memory problems, difficulties with multitasking, and reduced attention and concentration. Historically, cancer patients with these symptoms were often diagnosed with depression. Research over the past decade has revealed that many cancer patients experience such symptoms as a consequence of specific damage to the brain caused by either their tumor or their treatment. While radiation to the brain has long been linked to causing cognitive difficulties, the effects of chemotherapy on brain structure and function have only recently been discovered. We now know...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Brain and cognitive health Cancer Memory Radiation Source Type: blogs
Authors: Park JH, Kim HY, Jung YJ, Kim DI, Kim JY, Paik HJ Abstract Purpose: Core needle biopsy (CNB) is a widely used procedure for breast cancer diagnosis and analyzing results of immunohistochemistry (IHC). Several studies have shown concordance or discordance in IHC results between CNB and surgical specimens (SS). A double-check (CNB and SS) is inefficient and costly to perform a double-check on all patients. Therefore, it is important to determine which patients would benefit from a double-check. Methods: We collected the medical records of patients who underwent breast cancer surgery at Pusan National Uni...
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
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