Aquaporin 5 –1364A/C Promoter Polymorphism Is Associated with Pulmonary Inflammation and Survival in Acute Respiratory Distress Syndrome

Conclusions In acute respiratory distress syndrome attributable to bacterial pneumonia, the C-allele of theAQP5–1364A/C promoter polymorphism is associated with an attenuated pulmonary inflammation and higher 30-day survival. Thus, theAQP5 genotype impacts on inflammation and prognosis in acute respiratory distress syndrome.
Source: Anesthesiology - Category: Anesthesiology Source Type: research