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Condition: Influenza Intervention: Biological: Quadrivalent inactivated influenza vaccine (IIV) Sponsors: Stanford University; National Institutes of Health (NIH); National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting
ConclusionsThis study indicates that a substantial proportion of subjects with OA experience severe asthma and identifies potentially modifiable risk factors for severe OA that should be targeted in order to reduce the adverse impacts of the disease.
AbstractBackgroundIn wheat-dependent exercise-induced anaphylaxis (WDEIA), cofactors such as exercise, acetylsalicylic acid (ASA), alcohol or unfavorable climatic conditions are required to elicit a reaction to wheat products. The mechanism of action of these cofactors is unknown, but an increase of gliadin absorption has been speculated. Our objectives were to study gliadin absorption with and without cofactors and to correlate plasma gliadin levels with factors influencing protein absorption in healthy volunteers.MethodsTwelve healthy probands (six males, six females; aged 20 –56 years) ingested 32 g of g...
(MedPage Today) -- New evidence also presented on breastfeeding and development of atopic disease, asthma
Publication date: Available online 23 March 2019Source: Journal of Food Composition and AnalysisAuthor(s): Katsunari Ippoushi, Yoshimi Tanaka, Manabu Wakagi, Naoto Hashimoto, Yuko Takano-IshikawaAbstractPru p 1 and Pru p 3 are proteins found in peach (Prunus persica (L.) Batsch), and they are members of the pathogenesis-related protein 10 (PR-10) and non-specific lipid transfer protein (nsLTP) families, respectively. They are the main allergens of peach. In this paper, we describe a quantitative method for these proteins based on protein absolute quantification with liquid chromatography–tandem mass spectrometry, and...
Giving thyroid hormone replacement before conception didn't prevent miscarriages or other adverse pregnancy outcomes in euthyroid women with thyroid peroxidase antibodies, shows the TABLET trial.Medscape Medical News
This study aimed to investigate whether subcutaneous immunotherapy (SCIT) with Fagales pollen-containing extracts can improve the clinical symptoms of OAS in Korea. In total, 56 OAS patients were included: 19 subjects treated with SCIT, which included Fagales pollen extracts, and 37 not treated with immunotherapy (IT). We reviewed the patients' medical records and administered a telephone questionnaire at one point to assess baseline OAS features and changes in the patients' OAS and allergic rhinoconjunctivitis (ARC) symptoms after treatment. Only 12 patients who received SCIT and 15 patients that did not receive SCIT coul...
ConclusionsWe designed a highly specific 13 ‐item instrument for identifying SPT‐negative patients. It may be used in middle income countries where allergy testing is expensive, not reimbursed or few allergy clinics are available. We think that our idea is interesting, that needs further research.
Publication date: Available online 23 March 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Pooja Mehta, Zhaoxing Pan, Glenn T. Furuta, Bethany M. Kwan
Publication date: Available online 23 March 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Michele N. Pham, Michael Pistiner, Julie Wang