Miracle treatment or dangerous drug? Indonesian growers cash in on Kratom as it takes hold in the US
Many have died, suffered extreme reactions and overdoses to the morphine-like substance. It is grown in Indonesia were its use is banned but exports are allowed.
Last week we held a day-long conference at the Cato Institute devoted to exploring the strategy known as “harm reduction” to address the rising rate of drug overdose deaths and the spread of infectious diseases, such as hepatitis and HIV. In my remarks at the beginning and at the conclusion of the conference, I pointed out that the harms afflicting the drug-using community and their intimate contacts are the direct result of drug prohibition. Cato ’s Jeffrey Miron emphasized that point in a key presentation and discussed the success Portugal has had in reducing overdose deaths, HIV, hepat...
We describe the case of a 21-year-old black woman, with no prior psychiatric history, who developed a psychotic episode four days after she was started on isoniazid. This case highlights psychosis arising as a possible adverse effect of isoniazid and the importance of remaining vigilant when antituberculous therapy is started. PMID: 30906613 [PubMed]
Oklahoma's top court on Monday declined to delay a landmark trial set for May in a multibillion-dollar lawsuit accusing OxyContin maker Purdue Pharma LP and two other drugmakers of helping fuel an opioid abuse and overdose epidemic in the state.
More than 600 Ontarians died from opioid overdoses in the first six months of last year, new numbers reveal, as overdose prevention sites await word on whether they can continue to operate in the province beyond Sunday.
The objectives of this study were to evaluate this relationship and to assess the impact of PAD treatment on opiate use.
Phenazopyridine is a common, well tolerated medication with minimal side effects. Severe side effects are rare and include methemoglobinemia in setting of overdose, elderly patients, renal insufficiency and chronic use.Here we report a case of methemoglobinemia induced perioperative hypoxia in an adolescent patient without renal insufficiency or overdose which has not been reported previously. This case underscores the importance of judicious use of this medication in all patients but notably in pediatric patients and those with chronic lung disease.
Journal Name: Drug Metabolism and Personalized Therapy Volume: 34 Issue: 1 Pages: null-null
We present two cases of DNP toxicity that were treated with dantrolene.
The goals of this study are to describe clinical characteristics and risk factors for metabolic acidosis with hyperlactatemia in emergency department (ED) patients with acute metformin overdose.
Previous studies have shown that people who are hospitalized for treatment of mental illness have an elevated risk of suicide in the first few months after their discharge. Astudy inPsychiatric Services in Advance now reports that this immediate postdischarge period carries a higher risk not only of suicide, but also of death from other causes such as overdoses, accidents, and injuries. In addition, the findings suggest important opportunities for prevention.Ira R. Katz, M.D., Ph.D., of the Office of Mental Health and Suicide Prevention at the U.S. Department of Veterans Affairs (VA) and colleagues analyzed the records of ...