Millions of people in the UK must travel to GP surgeries in areas with 'toxic' air pollution

A third of people in England are registered at surgeries in areas of high pollution, a report from UK100 found. London is worst affected with 75% of patients affected, and 100% in some areas.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 20 March 2019Source: Saudi Journal of Biological SciencesAuthor(s): Steve Harakeh, Kalamegam Gauthaman, Peter N. Pushparaj, Ahmed Al-Hejin, Sulaiman M. Alfadul, Turki Al Amri, Salah Barnawi, Hadeel Al Sadoun, Ahmed A. Mirza, Esam AzharAbstractObesity is a chronic disorder that is associated with body mass index (BMI) of greater or equal to 30 kg/m2. The prevalence of obesity in the Kingdom of Saudi Arabia (KSA) is increasing at an alarming rate and is expected to reach 41% in men and up to 78% in women by 2022. Since chemokines are associated with involuntary weight loss, the objective of...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
This study was done to determine the degree of metals and heavy metals in some bee pollen sample as biological indicator for environmental pollution. Sample were collected from industrial, urban and agricultural areas of Jordan in year 2017. Eight metals (As, Cd, Cu, Mg, Pb, Ni, Se, and Zn) continents analyzed by using Inductively Coupled Plasma Optical Emission Spectrum, (ICP-OES).Results were statistically interpreted by using ANOVA analysis. Metals content in bee pollen from Jordan and China were determined within the following ranges (minimum-maximum mg/kg); Cu (copper): 11.338- 0.032, Zn (Zinc): 77.022-25.24, Ni (Nickel): 2.839-
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Publication date: May 2019Source: Fish &Shellfish Immunology, Volume 88Author(s): Gege Hu, Yijing Han, Dinglong Yang, Ruiwen Cao, Qing Wang, Hui Liu, Zhijun Dong, Xiaoli Zhang, Qianqian Zhang, Jianmin ZhaoAbstractFas-associated protein with death domain (FADD) is an essential element in cell death, and also implicates in cell cycle progression, inflammation and innate immunity. In the study, an FADD (designated as RpFADD) was identified and characterized from manila clam, Ruditapes philippinarum. Multiple alignments and phylogenetic analysis strongly suggested that RpFADD was a new member of the FADD family. The RpFADD...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: May 2019Source: Fish &Shellfish Immunology, Volume 88Author(s): Jeong Wan Do, Manoharan Saravanan, Sang-Eun Nam, Hyun-Jeong Lim, Jae-Sung RheeAbstractImmunotoxic effects of manganese (Mn) were investigated in the blood of the economically important marine fish, red seabream (Pagrus major) and black rockfish (Sebastes schlegelii) when exposed to different concentrations of Mn (0, 0.5, 1, and 2 mg L−1) for 14 days. During exposure, the levels of alternative complement activity in both fish were significantly lowered at 2 mg L−1 of Mn of exposure. Lysozyme activity was significantly d...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
In this study, we performed comparative transcriptome analysis among WSSV-infected shrimp under ammonia stress (LAV), WSSV-infected shrimp under normal water (LV), and normal shrimp under ammonia stress (LA) groups to identify the key genes and pathways involved in immunosuppression and increasing pathogen infection severity caused by ammonia toxicity in Litopenaeus vannamei. Totally, 526 significantly differential expressed genes (DEGs) were identified in LAV group compared to LV and LA groups, among which 270 genes were lost expressed and 67 genes uniquely expressed in the LAV group. According to the public functional re...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
The objective of this work was to investigate the effect of berberine (BBR) on the Cell viability, lipid accumulation, apoptosis, cytochrome c, caspase-9 and caspase-3 in lipid accumulation-hepatocytes induced by sodium palmitate in vitro. The lipid accumulation-hepatocytes (induced by 0.5 mM sodium palmitate for 24 h) were treated with 5 μM berberine for 12 h. Then, the Cell viability, intracellular triglyceride (TG) content, lipid peroxide (LPO), malonaldehyde (MDA) content, cytochrome c, caspase-9, caspase-3 and apoptosis were detected. Sodium palmitate decreased Cell viability and increased intracellular TG ...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
In this study, we used crucian carp administrated with dexamethasone to explore the effects of immunosuppressants on gut microbial communities and further evaluate the potential association between changes in gut microbiota and susceptibility to pathogens. The results of MANOVA based on the top 10 PCoA axis scores from unweighed/weighted UniFrac distances showed that administration of dexamethasone (P = 0.021) and the administration time (P = 0.027) had a significant impact on the gut microbial composition, regardless of pathogens infection status (P = 0.35). After administration with dexamethasone, the fish ha...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
ConclusionsTransmission to in vitro environment challenges cellular signalling and metabolism. The regulation of epigenetic remodelling maintains the balance between cellular plasticity and phenotype deviation. This preliminary research demonstrated reduced activity of genes responsible for epigenetic modifications of DNA and histones in in vitro expanded epidermal cells. This observation indicates that epigenome re-patterning in cultured epidermal cells is significantly less intensive than in the skin. Also, this observation may imply that after adaptation to in vitro conditions, the epigenome does not undergo extensive t...
Source: Advances in Medical Sciences - Category: Biomedical Science Source Type: research
Publication date: Available online 20 March 2019Source: Process BiochemistryAuthor(s): Mosi Dong, Tuoping Li, Suhong Li, Jia Guo, Yun Gong, Xin QiAbstractA yeast (Saccharomyces cerevisiae EBY100) surface displayed rice α-galactosidase II (YSD rice α-Gal II) was constructed. The optimum temperature and pH of YSD rice α-Gal II were 45 °C and 4.0-5.5, respectively. Ascorbic acid significantly increased the expression level of YSD rice α-Gal II by 5.7-fold, compared to control, indicating its importance in the production and application of YSD rice α-Gal II. Meanwhile, protective agents includ...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
Publication date: Available online 19 March 2019Source: Process BiochemistryAuthor(s): Jiabao Lyu, Zidan Li, Juncheng Men, Ruyun Jiang, Guilin Tang, Ye Zhou, Renjun GaoAbstractLipase A from Bacillus subtilis with modified aldehyde tags was successfully immobilized covalently on Fe3O4 monodispersed magnetite microspheres and greatly improves thermal stability. The properties of immobilized enzyme were investigated. Commercial magnetic particles embedded in SiO2 nanoparticles with size of 100 nm were amino-functionalised. Bacillus subtilis lipase A (BsLA) mutant contained eight changed amino acid, which improved the s...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
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