Medical News Today: What are examples of immunodeficiency disorders?
Immunodeficiency disorders, such as eczema, make it harder for the immune system to fight off infections and bacteria. Learn more about immunodeficiency disorders here.
Conclusions: The exposure to a large number of vaccine antigens derived from DTwP has no influence on the development of allergic diseases and atopic sensitization in children. PMID: 30206451 [PubMed]
ConclusionsMeasurement and control of disease risk factors should be carefully considered in observational studies of the safety of the immunization schedule.
Oral supplementation with probiotic bacteria is a promising alternative for allergy prevention. However, a recent meta-analysis has demonstrated that orally delivered bacteria only prevented the development of certain allergic manifestations, such as atopic eczema, but had limited efficacy on respiratory allergies.1 Similarly, oral delivery of the gram-negative probiotic bacterial strain Escherichia coli A0 34/86 (E coli O83; serotype O83:K24:H31; a commercially available oral live vaccine, Colinfant Newborn) to high-risk infants reduced development of atopic diseases in later life but had no beneficial effects on respiratory allergies.
Smallpox vaccination is associated with several potential cutaneous adverse reactions, ranging from benign self-limited hypersensitivity reactions to life-threatening eczema vaccinatum and progressive vaccinia. Acral papulovesicular eruption is a distinct presentation which has been described in U.S. military members following vaccination with the second generation smallpox vaccine ACAM2000. We characterize this unique eruption with 12 reported cases so far, as well as review previously described cutaneous adverse events associated with smallpox vaccination.
Condition: Atopic Dermatitis Interventions: Drug: Tralokinumab; Drug: Placebo; Biological: Tdap vaccine; Biological: Meningococcal vaccine Sponsor: LEO Pharma Not yet recruiting
Conclusions Measurement and control of disease risk factors should be carefully considered in observational studies of the safety of the immunization schedule.