Medical News Today: Breast cancer screening saved over 27,000 lives in 2018

A new study estimates that breast cancer mortality rates have fallen by approximately half in the United States in 2018, thanks to screening and therapy.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Breast Cancer Source Type: news

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This article falls into this emerging research by proposing a complete workflow, which was divided into three major steps. The first one consists in the fractionation of the same extract using four different chromatographic stationary phases and appropriated elution conditions to obtain five fractions for each column. The second step corresponds to the acquisition of chemical profiles using HPLC-HRMS analysis, and the biological evaluation of each fraction. The last step evaluates the links between the relative abundances of molecules present in fractions (peak area) and the global bioactivity level observed for each fract...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
We report on facile synthesis and characterization of phosphate-functionalized polymer dots (PDs) by doping tributyl phosphate (TBP) in a semiconducting polymer poly[9,9-dioctylfluorenyl-2,7-diyl)-co-1,4-benzo-{2,10-3}-thiadiazole)] (PFBT). Then, the prepared TBP@PFBT PDs were used to develop a very high sensitive probe for detection Fe3+, Cu2+ ions and Cytochrome c based on aggregation induced fluorescence off mechanism. The PDs exhibited a linear dynamic range for Fe3+ from 0.1 to 2 nM with a detection limit of 30 pM and for Cu2+ from 2.0 to 50.0 nM with a detection limit of 0.35 nM. Meanwhile, this probe showed a ...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 21 May 2019Source: MethodsAuthor(s): Lingtao Su, Guixia Liu, Juexin Wang, Dong XuAbstractDetecting cancer-related genes and their interactions is a crucial task in cancer research. For this purpose, we proposed an efficient method, to detect coding genes, microRNAs (miRNAs), and their interactions related to a particular cancer or a cancer subtype using their expression data from the same set of samples. Firstly, biclusters specific to a particular type of cancer are detected based on rectified factor networks and ranked according to their associations with general cancers. Secondly, codi...
Source: Methods - Category: Molecular Biology Source Type: research
Publication date: Available online 20 May 2019Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Xu Cheng, Dapeng Li, Min Sun, Le He, Yan Zheng, Xin Wang, Rupei TangAbstractChemotherapeutic drugs have a series of limitations in the conventional clinical treatments, mainly including serious adverse effects and multidrug resistance (MDR). Herein, we developed a pH-sensitive polymeric nanoparticle with using poly(ortho ester urethanes) copolymers for co-delivering doxorubicin (DOX) and pyrrolidinedithiocarbamate (PDTC) to settle these problems. Dual-drug-loaded nanoparticles were nano-sized (˜220 nm) with t...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
CONCLUSIONSThe main conclusion is that novice students do not seem to be able to accurately detect breast masses in a clinical setting even after training. On the basis of these results, we believe that a comprehension component in the current CBE testing is needed in addition to the current methods of testing. PMID: 31104050 [PubMed - in process]
Source: Work - Category: Occupational Health Authors: Tags: Work Source Type: research
Conditions:   Breast Cancer;   Aromatase Inhibitor;   Yoga;   Knee Pain Intervention:   Other: yoga Sponsor:   China Medical University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Breast Cancer Interventions:   Procedure: Metastasis biopsy;   Biological: Biomarkers blood, urine and microbiota samples;   Behavioral: Patient Reported Outcome (PRO) Sponsors:   Institut Cancerologie de l'Ouest;   European Regional Development Fund;   AstraZeneca;   Novartis;   Eli Lilly and Company Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Breast imaging software developer Volpara Solutions is highlighting a study...Read more on AuntMinnie.comRelated Reading: Volpara software awarded certification Volpara expands GE distribution agreement globally Volpara to launch updated mammo decision support at ECR Volpara gets FDA nod for new density uses ScreenPoint partners with Volpara
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
The American College of Radiology (ACR) Foundation announced the recipients...Read more on AuntMinnie.comRelated Reading: ACR to bring agenda to Capitol Hill Advocacy Day May 22 ACR, SBI rebuff new breast cancer screening guidelines SNMMI, ACR create clinical data registry Nvidia, ACR collaborate on AI for radiology ACR releases AI-LAB platform for AI development
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
CONCLUSIONS: Population-based registries should focus on specific measures for verifying the diagnosis of IBC since physicians may miss documenting the disease in medical records. This study may have implications for better reporting and documentation of IBC in hospital- and population-based cancer registries in Morocco and other similar countries. PMID: 31104003 [PubMed - as supplied by publisher]
Source: Breast Disease - Category: Cancer & Oncology Tags: Breast Dis Source Type: research
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