Chronic Kidney Disease Linked to Increase in Incident Diabetes

Renal damage, blood glucose level, family history--which was independently linked to incident T2DM in CKD? Read the study highlights.
Source: ConsultantLive - Category: Internal Medicine Authors: Tags: Kidney Disease Source Type: news

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Abstract: Diabetes mellitus is the leading cause of chronic kidney disease (CKD) in the US. An increasing number of glucagon-like peptide-1 receptor agonists are available for diabetes management. Differences between medications in this class, as well as limited data on patients with CKD, underscore the importance of a patient-centered approach to care.
Source: The Nurse Practitioner - Category: Nursing Tags: Feature: TYPE 2 DIABETES MELLITUS: CE Connection Source Type: research
The same underlying molecular and cellular damage of aging contributes to both calcification of blood vessel walls and the development of atherosclerosis, but researchers here argue that calcification can be considered on its own, an independent risk factor for cardiovascular dysfunction and mortality in later life. The presence of senescent cells is one of the common underlying factors that accelerates the progression of both atherosclerosis and calcification of blood vessels. This is due to the inflammatory signaling produced by these cells. That signaling distorts the behavior of macrophages trying to clear up deposits ...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Previous studies in general practice and hospital settings have identified that prescribing of non-insulin diabetes medications may be sub-optimal in people with type 2 diabetes (T2D) and renal impairment. Sin...
Source: BMC Family Practice - Category: Primary Care Authors: Tags: Research article Source Type: research
CONCLUSIONS: CVOTs and other studies confirm that the SGLT-2 inhibitors, mostly used in combination with other glucose-lowering drugs, offer several clinical benefits beyond improved glycemic control. These include reducing HHF risk and improving renal outcomes. HF and renal benefits are observed in individuals with and without established CVD, which may simplify therapeutic selection. Ongoing SGLT-2 inhibitor CVOTs will help clarify the potential of these drugs to treat T2D comorbid with different forms of HF (HF with preserved vs reduced ejection fraction) and different degrees of renal dysfunction, and in individuals wi...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
In conclusion, apart from the unmodifiable factors, avoiding prolonged urinary catheter placement, unnecessary prescriptions, and keeping good nutritional status may help to prevent UTI in home care patients.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
AbstractPurpose of ReviewOlder adults often live with chronic disease including diabetes and its complications. In this review, we examine the complexity and heterogeneity of older adults with diabetes and chronic kidney disease, explore the nuances in their diabetes-related monitoring, and discuss their best diabetes management.Recent FindingsAlthough there remains an overall lack of studies in older adults with diabetes and chronic kidney disease, recent reports have highlighted their vulnerabilities. These individuals face an increased risk of cognitive impairment and dementia, frailty, dysglycemia, polypharmacy, declin...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
AbstractThe aim of the study was to determine the clinical and biochemical characteristics especially cystatin C and the association of angiotensin type I receptor (AT1R) gene polymorphism with normoalbuminuric chronic kidney disease (NACKD) among South Indian type 2 diabetes (T2DM) population.Material and methodsThe study comprised of 308 (M:F 190:118) subjects with T2DM categorized into three groups. Group I: T2DM patients without albuminuria (NA) and estimated glomerular filtration rate (eGFR)>  90 ml/min/1.73m2 (n = 110); group II: T2DM patients with albuminuric chronic kidney disease (CKD) with eGFR
Source: International Journal of Diabetes in Developing Countries - Category: Endocrinology Source Type: research
This is a case report of a man in his 60s with stage 3 chronic kidney disease, hypertension, hyperlipidemia, type 2 diabetes, bladder and kidney cancer, and depression who underwent hypoglossal nerve stimulator implantation and subsequently demonstrated a Cheyne-Stokes breathing pattern.
Source: JAMA Otolaryngology - Head and Neck Surgery - Category: ENT & OMF Source Type: research
ConclusionsResults suggest that telemedicine has a positive impact on self-management processes and on HbA1c levels. However, future evaluative reviews are necessary to confirm and quantitate the impact of telemedicine on self-management processes and primary studies are necessary to evaluate its impact on long term clinical outcomes.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
In conclusion, a model using real-world electronic medical records (EMR) data can accurately predict future kidney functions and provide clinical decision support. PMID: 30768948 [PubMed - as supplied by publisher]
Source: Mathematical Biosciences - Category: Statistics Authors: Tags: Math Biosci Source Type: research
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