Intense IV blood glucose control ‘doesn’t improve stroke outcomes’

Intravenous insulin does not improve stroke outcomes compared to standard blood glucose control using insulin shots, according to researchers.
Source: Nursing Times - Category: Nursing Source Type: news

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Conclusions: The TMST has been widely used since first introduced, albeit not always as originally described. There is considerable evidence for the validity of the test, but its reliability and responsiveness are not yet firmly established.
Source: Journal of Geriatric Physical Therapy - Category: Physiotherapy Tags: Systematic Review Source Type: research
Conclusions: Higher serum albumin is associated with lower HT risk in a dose-dependent manner in AIS patients younger than 60 years.Cerebrovasc Dis 2019;47:88 –94
Source: Cerebrovascular Diseases - Category: Neurology Source Type: research
In this study, the Cystathionine β -synthase promoter methylation levels of hypertensive and stroke participants were both higher than that of the healthy individuals (median percentages of the methylated reference were 50.61%, 38.05% and 30.53%, respectively, all p
Source: Clinics - Category: General Medicine Source Type: research
Publication date: April 2019Source: Annals of Emergency Medicine, Volume 73, Issue 4Author(s): Clifford L. Freeman, Tyler W. Barrett
Source: Annals of Emergency Medicine - Category: Emergency Medicine Source Type: research
CONCLUSIONS: This study confirms that the guidelines are routinely followed in clinical practice in this rural population. PMID: 30889960 [PubMed - in process]
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
Publication date: Available online 21 March 2019Source: Anaesthesia &Intensive Care MedicineAuthor(s): Michael Stallard, Indran RajuAbstractCarotid endarterectomy (CEA) is a surgical procedure to prevent strokes in patients with atheromatous disease at the carotid bifurcation. The effectiveness of CEA has been established in large clinical trials. Patients should have surgery performed within 2 weeks from the onset of symptoms. This time frame presents challenges to the anaesthetist and surgeon in terms of risk stratification and optimization of patients. Optimization includes blood pressure control and use of antiplat...
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 20 March 2019Source: Neuroscience LettersAuthor(s): Wanyi Jia, Yasmine Kamen, Helena Pivonkova, Ragnhildur T. KáradóttirAbstractBrain tissue undergoes substantial activity-dependent reorganisation after stroke due to neuronal plasticity, leading to partial functional recovery in patients. Concurrent myelin repair is crucial for proper neuronal network function and reorganisation. Myelin repair after stroke might occur as myelin plasticity or as remyelination through the recruitment and differentiation of oligodendrocyte precursor cells (OPCs), which become myelin-forming oli...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 20 March 2019Source: Neurochemistry InternationalAuthor(s): Hongli Dong, Yuanyuan Qin, Yuyu Huang, Dongliang Ji, Feng WuAbstractParkinson's disease (PD) is the second most common neurodegenerative disorder characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). Rupture of lysosome is a major cellular stress condition leading to cell death in PD. We have previously shown that environmental oxidative toxins could impair autophagic flux and lysosomal functions in PD. Poloxamer 188 (P188) is an amphipathic polymer which has cytoprotecti...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
The objective of this retrospective study was to investigate which cases are more likely to experience vasospasm after thrombectomy with stent retrievers.MethodsWe included 29 patients diagnosed with acute cardiogenic cerebral embolism who were treated with stent retrievers at our facility from December 2014 to December 2017. Atherothrombotic brain infarction cases were excluded because it was difficult to evaluate for vasospasms. Vasospasm was defined as reversible arterial narrowing of
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 20 March 2019Source: Journal of Clinical NeuroscienceAuthor(s): Pouria Moshayedi, Shashvat M. Desai, Ashutosh P. JadhavAbstractParallel to a more widespread application of endovascular neurothrombectomy in acute ischemic stroke, it is critical to understand the nature and management of associated complications, including wire perforation of the middle cerebral artery (MCA). Sacrifice of the perforated vessel may be necessary to avoid fatal intra-cranial hemorrhage. Here we describe a case of right MCA distribution ischemia complicated by a right MCA perforation. Using super selective inje...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
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