Local Alcohol Profiles for England data update

This latest data release includes: admission episodes for alcohol-related conditions (Narrow), admission episodes for alcohol-related conditions (Broad), admission episodes for alcohol-specific conditions. This release includes the above indicators broken down by age group and cause where appropriate and are available at local authority level as well as for England, the regions, and various inequality groups. The Local Alcohol Profiles have been published on an annual basis since 2006. These profiles have been designed to help local government and health services assess the effect of alcohol use on their local populations. They will inform commissioning and planning decisions to tackle alcohol use and improve the health of local communities.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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ConclusionPlasmalogens could be a potential biomarker for evaluating the early stages of oxidation in NASH.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Conclusion Before turning to the temporary relief you may find in prescription medication, illicit drugs, or alcohol, strongly consider trying one of these free, proven methods for relieving stress and curbing anxiety. Matthew Boyle is the Chief Operating Officer of Landmark Recovery, a growing chain of drug and alcohol rehab centers in Oklahoma and Kentucky. Matthew graduated from Duke University in 2011 Summa Cum Laude with a Bachelor of Arts degree and has worked in the healthcare industry ever since, creating a holistic treatment model that supports patients in the pursuit of achieving lifelong sobriety.You've read...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: depression featured happiness self improvement breathing de-stress exercise meditation pickthebrain Source Type: blogs
Abstract Facing the problem of a growing number of analyses, the need for using simple equipment appears. Smartphone-based optical detection is one of the most widely applied ideas nowadays. A personal device such as a smartphone equipped with a camera is affordable even in the source-limited places. After a simple modification, providing the light source of both defined properties and orientation, a smartphone may become an efficient analytical device. In this work we present a uniform methodology of such a modification, offering a complete hand-held device for fluorometric measurements. Inducing the fluorescence...
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research
In this study, a gas-imaging system (sniff-cam) that can be used to simultaneously image the concentration distribution of multiple VOCs, namely, ethanol (EtOH) and acetaldehyde (AcH), was developed. The sniff-cam was based on the pH-dependent redox reactions of nicotinamide adenine dinucleotide (NAD)-dependent alcohol dehydrogenase (ADH). The sniff-cam was constructed with a camera, two ADH-immobilized meshes, and a UV-LED array sheet. The ADH-immobilized mesh containing a solution of the oxidized form of NAD (NAD+) or reduced form (NADH) was used as an EtOH-imaging mesh and an AcH-imaging mesh, respectively. The distribu...
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research
Abstract Attempts to perform the OsO4-catalyzed enantioselective base-free aminohydroxylation of β,β-disubstituted enoates are described. Low yields and racemic products were obtained in the presence of standard chiral ligands, suggesting the occurrence of a "Second Cycle" process due to slow hydrolysis of the amino alcohol product from the Os metal center. Support for this hypothesis was provided by the slightly improved enantioselectivity (60:40 er) obtained with an amino alcohol ligand. Based on density functional theory calculations, it is proposed that the lack of significant enantioselect...
Source: Tetrahedron - Category: Chemistry Authors: Tags: Tetrahedron Source Type: research
ConclusionMost common site of colorectal carcinoma left colon, which present in 61.97%. There is increase in new cases detection of colorectal carcinoma from 2013 to 2016. Advanced stages cancer were most common stages description as IIIA, IIIB, IIIC and IV in 12.67%, 16.90%, 19.72% and 15.49%. The common histopathological pattern is differentiated adenocarcinoma as 53.52%.ResumoIntroduçãoO carcinoma colorretal é o câncer mais comum do trato gastrointestinal. É o terceiro tipo de câncer mais observado no sexo masculino mundialmente, atrás dos cânceres de pulmão e ...
Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
ConclusionsHPV+ OPSCC was more prevalent in white males with a high number of lifetime sexual partners, as expected. Careful evaluation revealed other findings of significance that are not generally associated with this population. Half of our patients had significant historical tobacco and alcohol consumption. One quarter of patients had a history of another malignancy. These findings highlight the importance of taking a comprehensive history when determining appropriate treatment or designing future de-escalation trials in HPV+ OPSCC.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
Publication date: Available online 18 February 2019Source: The Lancet PsychiatryAuthor(s): Yueqin Huang, Yu Wang, Hong Wang, Zhaorui Liu, Xin Yu, Jie Yan, Yaqin Yu, Changgui Kou, Xiufeng Xu, Jin Lu, Zhizhong Wang, Shulan He, Yifeng Xu, Yanling He, Tao Li, Wanjun Guo, Hongjun Tian, Guangming Xu, Xiangdong Xu, Yanjuan MaSummaryBackgroundThe China Mental Health Survey was set up in 2012 to do a nationally representative survey with consistent methodology to investigate the prevalence of mental disorders and service use, and to analyse their social and psychological risk factors or correlates in China. This paper reports the p...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 18 February 2019Source: NeuroscienceAuthor(s): Katherine Najera, B. Matthew Fagan, Peter M. ThompsonAbstractSynaptosomal Associated Protein-25 kilodaltons (SNAP-25) is an integral member of the SNARE complex. This complex is essential for calcium-triggered synaptic vesicular fusion and release of neurotransmitters into the synaptic cleft. In addition to neurotransmission, SNAP-25 is associated with insulin release, the regulation of intracellular calcium, and neuroplasticity. Because of SNAP-25's varied and crucial biological roles, the consequences of changes in this protein can be seen ...
Source: Neuroscience - Category: Neuroscience Source Type: research
Conditions:   Alcohol Use Disorder;   Couples Interventions:   Combination Product: Oxytocin & Therapy;   Combination Product: Placebo & Therapy Sponsors:   Medical University of South Carolina;   National Institute on Alcohol Abuse and Alcoholism (NIAAA) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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