Lipid profile in type 2 patients with diabetes from Tlemcen: A Western Algerian population

In this study, we performed a transversal investigation on 100 patients with diabetes type 2 and 10 controls with no clinical history of diabetes. A questionnaire was developed with the anthropometric data and biochemical following values: fasting blood glucose (GLU), total cholesterol (TCHOL), triglycerides (TRG), high-density lipoproteins (HDL-C) and glycosylated hemoglobin (GHbA1c) and calculated levels of low-density lipoprotein (LDL-C). We describe further the characteristics of lipid parameters in the study population. To this end, we analyzed the data using descriptive statistics by mean and standard deviation.According to our results, a female predominance was recorded in our population with a high breakdown for the age group between 51 and 71 years. The average blood glucose was 206 mg/dl, and the average glycated hemoglobin was 8.2%. The majority of diabetic patients had a lipid profile considered normal. 60% of the patients had cholesterol values less than 200 mg/dl; 57.7% had TG values less than 150 mg/dl; 54% had HDL-C values more than 40 mg/dl and 87.5% had LDL-C values less than 160 mg/dl.Our study shows that the lipid profile of a diabetic population of the Tlemcen region is normal and has no lipid abnormality. It is different from that in the West, where the lipid profile is lower but at inferior proportions.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research

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ConclusionThere are conflicting results about the effect of SGLT2 inhibitors on the lipid profile in the literature. According to our data, dapagliflozin has positive effects on lipid profile as weight and glycemic control and it is well tolerated. Therefore, dapagliflozin therapy is beneficial because of the positive change in lipid profile and weight loss in diabetic patients with overweight and hyperlipidemia.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionThe High rate of metabolic syndrome among obese adolescents is alarming.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionSerum adiponectin level can be a good predictor of diabetic nephropathy in patients with type 2 diabetes mellitus.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionThe High rate of metabolic syndrome among obese adolescents is alarming.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionSerum adiponectin level can be a good predictor of diabetic nephropathy in patients with type 2 diabetes mellitus.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Metabolic syndrome (MS) is a constellation of risk factors, which, when not treated, leads to the development of type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD). It is a prevalent condition, which is associated with the growing epidemic of sedentary lifestyle[1]. MS is diagnosed when at least three out of five following risk factors are present: central obesity, elevated serum triglycerides, low HDL cholesterol concentrations, impaired fasting glucose and elevated systolic (SBP) or/and diastolic blood pressure (DBP)[2].
Source: Maturitas - Category: Primary Care Authors: Source Type: research
Conclusion The relationships between the potency of 5-HT2C blockade and hypertriglyceridemia and the potency of M3 blockade and glucose intolerance were shown in clinical setting. Receptor-binging profiles might be useful to estimate metabolic effect of antipsychotics-treatment. References Meyer JM, Davis VG, Goff DC, et al. Change in metabolic syndrome parameters with antipsychotic treatment in the CATIE Schizophrenia Trial: prospective data from phase 1. Schizophr Res. 2008;101: 273–286. Salvi V, Mencacci C, Barone-Adesi F. H1-histamine receptor affinity predicts weight gain with antidepressants. Eur Neuropsychoph...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Letters to the Editor Asenaprine clozapine olanzapine schizophrenia Source Type: research
This study aimed at investigating whether Nrg4 is associated with MetS in nT2DM patients. A total of 311 patients with nT2DM were recruited. Plasma Nrg4 concentration was determined by ELISA. Plasma Nrg4 concentration was lower in nT2DM patients with MetS than in nT2DM patients without MetS (P = 0.001). Nrg4 concentration showed negative correlations with most of the analyzed indicators of MetS. MetS was less prevalent among subjects in the highest quartile of plasma Nrg4 concentration than among those in the lowest quartile (P
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Conclusion Serum adiponectin level can be a good predictor of diabetic nephropathy in patients with type 2 diabetes mellitus.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Metabolic syndrome, also known as syndrome X, which was first described in the 1950s, is a disorder characterized by central obesity, hypertension, hyperglycemia, and dyslipidemia. With insulin resistance being one of the pathogenetic factors, it predisposes individuals to the development of type 2 diabetes mellitus and cardiovascular disease.1 However, metabolic syndrome in children and adolescents has no universally accepted definition. The majority of current definitions have been adapted from the adult criteria developed by the National Cholesterol Education Program.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Editorial Source Type: research
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