Transcranial sonography identifies Parkinson's earlier

Transcranial sonography offers clinicians a viable way to diagnose Parkinson's...Read more on AuntMinnie.comRelated Reading: Preclinical PET sheds light on Parkinson's abnormalities fMRI links brain disruptions to Parkinson's hallucinations DWI-MRI shows vision changes could predict Parkinson's DTI-MRI sheds light on Parkinson's disease FDG-PET predicts survival in Parkinsonian syndrome
Source: Headlines - Category: Radiology Source Type: news

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INTRODUCTION: Postural instability during walking and tripping over obstacles are the main causes of falls in people with Parkinson's disease (PD). Preliminary limited evidence suggests that the length of the prospective follow-up period affects falls pred...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Many diseases are related to age, among these neurodegeneration is particularly important. Alzheimer's disease Parkinson's and Glaucoma have many common pathogenic events including oxidative damage, Mitochondrial dysfunction, endothelial alterations and ch...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Authors: Alzahrani S, Ezzat W, Elshaer RE, Abd El-Lateef AS, Mohammad HMF, Elkazaz AY, Toraih E, Zaitone SA Abstract Strong evidence proposes that brain oxidative DNA damage and microglia activation contribute to Parkinson's disease (PD) pathogenesis. Traditional therapeutic regimens for PD can only relieve the symptoms. Tribulus terrestris (T. terrestris), a flowering plant from family Zygophyllaceae, is used in traditional medicine for treating different disorders and exerts neuroprotective and antioxidant effects in experimental models. The current study attempted to test whether treatment with T. terrestris sta...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Publication date: Available online 23 March 2019Source: Journal of PhysiotherapyAuthor(s): Prudence Plummer
Source: Journal of Physiotherapy - Category: Physiotherapy Source Type: research
In this study, we investigated the ameliorative effect of baicalein with low dose L-DOPA (25 mg/kg) on the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced Parkinsonism. The gait variability was assessed by a computer-assisted gait analysis system Catwalk. The results showed that MPTP challenged mice had significant gait deficits on dynamic paw function and posture stability. L-DOPA reversed the MPTP induced gait deficits and the effect was positively dose-dependent. The combined treatment of baicalein and under threshold dose of L-DOPA significantly improved gait functions, compared with exclusive low dose L-...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
ConclusionsThe main purpose of the current work is to focus on important topics about the microencapsulation of polyphenols, studying the specific case of the Sambucus Nigra L. extracts, including the description of the most important extraction methods for plant samples and of the encapsulation techniques and wall materials used to encapsulate polyphenols. It was also made an approach to the release tests involved in the release phenomenon of the bioactive compounds from the natural resources, including its mechanisms, simulated release media and kinetics.Graphical abstract
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
Source: Health Marketing Quarterly - Category: International Medicine & Public Health Authors: Source Type: research
AbstractParkinson ’s disease (PD) is a chronic, progressive condition affecting around 1% of the population older than 60 years. Upon long-term treatment with levodopa, the mainstay of treatment in PD, most patients, especially younger ones exposed to higher doses, will experience symptoms related to end-of-dose d eterioration, peak-dose dyskinesias, and other motor fluctuations. Therapeutic strategies are grounded on modification of oral levodopa pharmacokinetics to extend levodopa benefit and development of new routes of drug delivery (e.g., levodopa/carbidopa intestinal gel infusion) or long-acting formula ti...
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
This study aimed at evaluating brain glucose metabolism, measured by [18F]FDG-PET, in patients affected by iRBD and compared to Parkinson's Disease (PD), Lewy Body Dementia (DLB), Alzheimer's Disease (AD), and controls.
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Source Type: research
To evaluate the association between anemia and Parkinson's disease risk (PD) in men and women.
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Source Type: research
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