Exenatide once-weekly improves metabolic parameters, endothelial dysfunction and carotid intima-media thickness in patients with type-2 diabetes: an 8-month prospective study

Type 2 diabetes mellitus is a multiple etiology metabolic disorder characterized by chronic hyperglycemia in subjects with insulin resistance. This chronic hyperglycemia results in altered insulin secretion, reduced glucose utilization, and increased liver glucose production [1,2]. Persons with type 2 diabetes mellitus are usually overweight and obese [3] and they frequently have high blood pressure, dyslipidemia and, ultimately, a significantly elevated risk of cardiovascular (CV) diseases [4].

Source: Diabetes Research and Clinical Practice - February 10, 2019 Category: Endocrinology Authors: Angelo Maria Patti, Dragana Nikolic, Antonio Magan-Fernandez, Rosaria Vincenza Giglio, Giuseppa Castellino, Roberta Chianetta, Roberto Citarrella, Egle Corrado, Francesca Provenzano, Vincenzo Provenzano, Giuseppe Montalto, Ali A. Rizvi, Manfredi Rizzo Source Type: research