Is exposure to lead a risk for arthritis? Study finds correlation between lead in the blood and knee osteoarthritis

(Natural News) Knee osteoarthritis is a menace that plagues millions of people every single day. Since it’s something that affects so many people’s lives, scientists and other experts are always on the lookout for new and improved ways of administering treatment than currently known and available methods. One group of Egyptian researchers has now contributed...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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AbstractPurposeTo describe a surgical technique in correcting valgus deformity during total knee replacement and evaluate medium-term clinical outcomes.MethodsThis was a retrospective consecutive series of total knee replacement for severe valgus deformity of patients who underwent a lateral ligament complex release with a sliver osteotomy of the lateral femoral condyle with a minimum 1-year follow-up and recording objective and patient-reported outcome measures.ResultsTwenty-three patients (25 knees) were included with median follow-up of 5  years (range 1–15 years) and average age 67.7 years (range 4...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - Category: Orthopaedics Source Type: research
Abstract The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases. Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small molecule inhibitors have been used for the therapeutic targeting of lncRNAs. During the last decade, phytochemicals and nutraceuticals have been explored for their potential against lncRNAs. The common lncRNAs known to be modulated by phytochemicals include ROR, PVT1, HOTAIR, MALAT1, H19, MEG3, PCAT29, PANDAR, NEAT1, and GAS5. The phytochemicals such as curcumin, resveratrol, sulforaphane, berberine, EGCG, and gambogic acid have been ...
Source: Cellular and Molecular Life Sciences : CMLS - Category: Cytology Authors: Tags: Cell Mol Life Sci Source Type: research
Conditions:   Shoulder Pain;   Shoulder Osteoarthritis;   Shoulder Arthritis Interventions:   Device: Stemmed shoulder arthroplasty, Biomet Comprehensive® Total Shoulder System.;   Device: Stemless shoulder arthroplasty, Biomet Comprehensive® Nano Shoulder System. Sponsors:   Zealand University Hospital;   Hvidovre University Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
THURSDAY, March 14, 2019 -- Knee pain is not associated with daily walking levels in individuals with mild-to-moderate, symptomatic knee osteoarthritis (KOA), according to a study published online March 6 in Arthritis Care&Research. Nicholas...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
(Reuters Health)—Patients with knee osteoarthritis (OA) can add hip-strengthening exercises to their workout to improve the ability to walk and maybe reduce pain, according to a research review. Based on pooled data from eight clinical trials with a total of 340 patients, hip strengthening exercises involving weights or elastic bands would help the most, the... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Osteoarthritis Exercise hip knee Knee Osteoarthritis (OA) knee pain walking weight training Source Type: research
Condition:   Osteoarthritis Intervention:   Other: Hip school or Tai CHi for arthritis Sponsor:   Lund University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionThe current evidence indicates that berberine may be effective in preventing musculoskeletal disorders. However, findings from in vitro and in vivo investigations await further validation from human clinical trial.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Patients with knee osteoarthritis can add hip-strengthening exercises to their workout to improve the ability to walk and maybe reduce pain, according to a research review.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Rheumatology News Source Type: news
We report that in human primary articular chondrocytes, erythromycin, a well-known macrolide antibiotic, had the ability to inhibit pro-inflammatory cytokine Interleukin 1β (IL-1β)-induced catabolic gene expression and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) activation. Furthermore, erythromycin inhibited monosodium iodoacetate (MIA)-induced joint inflammation and cartilage matrix destruction in mice, an arthritis model that reflects the inflammatory and cartilage matrix loss aspects of OA. EM900, an erythromycin-derivative lacking antibiotic function, had the same activity as...
Source: Biochemical Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Biochem Pharmacol Source Type: research
CONCLUSIONS The arthritic process affecting the knee joint results in altered kinematics and biomechanics of the affected knee joint. This is manifested at both the axial and sagittal plane, when the kinematics fails to equal that of the healthy joint. The implantation of the medial unicompartmental knee arthroplasty improves the kinematics of the knee joint and helps achieve the requested values and stabilises the knee joint. Key words:medial gonarthrosis, unicompartmental knee arthroplasty, knee joint kinematics. PMID: 30843511 [PubMed - in process]
Source: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca - Category: Orthopaedics Tags: Acta Chir Orthop Traumatol Cech Source Type: research
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