Dietary interventions in Fibromyalgia: a systematic review.

Dietary interventions in Fibromyalgia: a systematic review. Ann Med. 2019 Feb 08;:1-29 Authors: Silva AR, Bernardo A, Costa J, Cardoso A, Santos P, Mesquita MF, Vaz Patto J, Moreira P, Silva ML, Padrão P Abstract Fibromyalgia (FM) is a chronic non-degenerative disease, whose nutritional therapy seems controversial. This systematic review aimed to synthesize the knowledge about the effect of dietary interventions on patient reported outcomes (PRO) and inflammation in patients with FM. Six electronic databases - PubMed, BioMed Central, Cochrane library, EMBASE, LILACS and ISI - were searched for clinical trials, in which a dietary intervention in patients with FM diagnosed was conducted. Quality of evidence assessment was measured in accordance to GRADE methodology. Seven clinical trials - 3 randomized controlled trials, 1 unrandomized clinical trial and 3 uncontrolled clinical trials, were identified. Dietary approaches included gluten-free diet (n = 1), raw vegetarian diet (n = 2), low Fermentable Oligo-, Di- and Monossacharides, Alcohols and Polyols (FODMAPs) diet (n = 1), hypocaloric diet (n = 2) and monosodium glutamate- and aspartame-free diet interventions (n = 1). The major PRO were pain and functional repercussion, with 5 out of 7 studies reporting an improvement. The progress in secondary outcomes was reported for fatigue (2/5 studies), sleep quality (2/3 studies), depression and anxiety (3/6 studies), qu...
Source: Annals of Medicine - Category: Internal Medicine Tags: Ann Med Source Type: research