Medical News Today: Diabetes: Could a pill replace insulin injections?

Insulin injections are part of daily blood glucose management for many people with type 2 diabetes. Now, a new pill could spell the end for injections.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Diabetes Type 2 Source Type: news

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Publication date: Available online 18 March 2019Source: Redox BiologyAuthor(s): Jiawei Yin, Xiaoqian Wang, Shuzhen Li, Yalun Zhu, Sijing Chen, Peiyun Li, Cheng Luo, Yue Huang, Xiaoqin Li, Xueting Hu, Wei Yang, Wei Bao, Zhilei Shan, Liegang LiuAbstractAimsTo examine the associations of plasma copper concentrations and superoxide dismutase 1 (SOD1) polymorphisms as well as their gene-environment interaction with newly diagnosed impaired glucose regulation (IGR) and type 2 diabetes (T2D).MethodsWe performed a large case-control study in 2520 Chinese Han subjects: 1004 newly diagnosed T2D patients, 512 newly diagnosed IGR pati...
Source: Redox Biology - Category: Biology Source Type: research
Conditions:   Diabetes;   Obesity Interventions:   Other: tDNA-MI group;   Other: tDNA-CC group;   Other: UC group Sponsor:   International Medical University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Moderate levels of resistance training should be encouraged to reduce the risk of developing type 2 diabetes, US findings suggest, although conversely, high-strength training may negate the effect.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
Publication date: Available online 18 March 2019Source: Molecular MetabolismAuthor(s): Amna Khamis, Mickaël Canouil, Afshan Siddiq, Hutokshi Crouch, Mario Falchi, Manon von Bulow, Florian Ehehalt, Lorella Marselli, Marius Distler, Daniela Richter, Jürgen Weitz, Krister Bokvist, Ioannis Xenarios, Bernard Thorens, Anke M. Schulte, Mark Ibberson, Amelie Bonnefond, Piero Marchetti, Michele Solimena, Philippe Froguel
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
ConclusionA large number of people's dietary habit has strong association with diabetic risk profile among type-2 diabetic patients.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionThe literature reports lower concentrations of systemic sTWEAK in T2DM which may be comparable to our observations in CP + T2DM when compared to health and its negative correlation with all the parameters suggesting an association with both clinical periodontal parameters and glycemic levels. However, serum sTWEAK levels may not be necessarily elevated in periodontitis as previously reported, and hence has the potential to be studied extensively for clarification with its association with T2DM.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Resumo Investigar os fatores associados ao controle glic êmico de pessoas com diabetes mellitus (DM). Estudo transversal realizado com 746 pessoas com DM tipo 2 e 40 anos ou mais de idade. Elegeu-se as seguintes variáveis: socioeconômicas, dados clínicos, estilo de vida e o risco para o desenvolvimento de úlceras nos pés. A coleta dos dados ocorreu por meio de entrevista, análise do prontuário e exame clínico dos membros inferiores. Utilizou-se o modelo de regressão múltipla de Poisson para determinação das razões de preval&ecir...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
This study, titled “UK First NHS EndoBarrier Service for Advanced Type 2 Diabetes and Obesity: One-Year Outcomes in All Patients Treated,” is based on data collected from the first implant in October 2014 to the last explant in November 2018, a total patient population of 61. The primary outcome of HbA1c, weight, CVD risk factors and alanine aminotransferase (ALT — a liver fat measure) show a significant reduction at explant compared to baseline values. Of the 61 patients studied, 35 were on insulin prior to treatment. At explant, 10 of the 35 (28.6%) discontinued their...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
SUMMARY Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are drugs that act by maintaining glycosuria. Recent studies have shown promising effects of these in the treatment of type 2 diabetes mellitus (DM2). However, there may be an increased risk of developing urinary tract infections (UTIs) in patients treated with these. Our study aims to analyze the association between the risk of UTI in patients treated with SGLT2i. A systematic review of the literature was carried out by randomized clinical trials, totalizing at the end of the selection 23 articles that were statistically evaluated. The incidence of UTI was general...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
New research reveals that the only two medications approved for pediatric type 2 diabetes do not prevent rapid progression of prediabetes or recent onset type 2 diabetes in young people with the disease; however, analyses comparing metabolic tests of adults in a companion study and the youth study participants are helping scientists understand how the disease differs with age, which may one day lead to better treatment approaches.
Source: NIDDK News - Category: Endocrinology Source Type: news
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