Physiopathological premises to Nuclear Medicine Imaging of pancreatic neuroendocrine tumours.

CONCLUSIONS: Although agonists usually provide efficient internalization, also somatostatin antagonists (SS-ANTs) could be used for imaging and therapy. Peptide receptor radionuclide therapy (PRRT) represents the most successful option for targeted therapy. The theranostic model based on SSTR doesn't work in insulinoma, in which different radiotracers such as F-18 FluoroDOPA or tracers for the glucagon-like peptide-1 receptor have to be preferred. PMID: 30727940 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30727940?dopt=Abstract

Source: Current Radiopharmaceuticals - February 10, 2019 Category: Radiology Tags: Curr Radiopharm Source Type: research