Molecular effects of dietary fatty acids on brain insulin action and mitochondrial function.

Molecular effects of dietary fatty acids on brain insulin action and mitochondrial function. Biol Chem. 2018 Dec 01;: Authors: Chudoba C, Wardelmann K, Kleinridders A Abstract The prevalence of obesity and its co-morbidities such as insulin resistance and type 2 diabetes are tightly linked to increased ingestion of palatable fat enriched food. Thus, it seems intuitive that the brain senses elevated amounts of fatty acids and affects adaptive metabolic response, which is connected to mitochondrial function and insulin signaling. This review will address the effect of dietary fatty acids on brain insulin and mitochondrial function with a special emphasis on the impact of different fatty acids on brain function and metabolism. PMID: 30730834 [PubMed - as supplied by publisher]
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research