Objective assessment of dermal fibrosis in cutaneous scarring: using optical coherence tomography, high frequency ultrasound and immuno-histo-morphometry of human skin.

CONCLUSIONS: Time-matched comparison images between H&E, OCT and HFUS demonstrated that epidermal/dermal structures were better distinguished by OCT. HFUS enabled deeper visualisation of the dermis including the subcutaneous tissue. Choice of device was relevant upon the depth of scar type, parameters to be measured and morphological detail required in order to provide better objective quantitative indices of the quality and extent of dermal fibrosis. This article is protected by copyright. All rights reserved. PMID: 30729516 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research