Underutilized cardiac MRI stress test predicts mortality

A stress test with cardiac MRI can do more than simply assess heart function....Read more on AuntMinnie.comRelated Reading: SPECT, MRI together advance arrhythmia treatment Imaging modalities differ in assessing key heart metric New protocol enables faster, cheaper cardiac MRI scans Cardiac MRI offers prognosis for hard-to-find infarctions MRI technique could let cardiac patients breathe easier
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Publication date: Available online 23 March 2019Source: Pharmacological ResearchAuthor(s): Ahmed AlTurki, Riccardo Proietti, Vincenzo Russo, Tarvinder Dhanjal, Prithwish Banerjee, Vidal EssebagAbstractImplantable cardioverter-defibrillators (ICDs) have revolutionized the primary and secondary prevention of patients with ventricular arrhythmias. However, the adverse effects of appropriate or inappropriate shocks may require the adjunctive use of anti-arrhythmic drugs (AADs). Beta blockers are the cornerstone of pharmacological primary and secondary prevention of ventricular arrhythmias. In addition to their established effi...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Authors: Sztechman D, Czarzasta K, Cudnoch-Jedrzejewska A, Szczepanska-Sadowska E, Zera T Abstract In the review we discuss the role of mineralocorticoid receptors (MRs) in regulation and pathological remodelling of the cardiovascular system and the therapeutic potential of pharmacological targeting of MRs in cardiovascular diseases. MRs are expressed in organs involved in cardiovascular homeostasis: brain, heart, kidneys and vessels. The excessive activation of MRs has deleterious effects on the cardiovascular system through sympatho-excitation, elevated salt appetite, and renal retention of salt with consequent p...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
ConclusionATP is moderately effective for the treatment of monomorphic VTs in HCM patients. However, the rate of appropriate ATP therapies is low, ATP is often prematurely delivered, and ATP ‐induced arrhythmia degeneration is of concern.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: DEVICES Source Type: research
There are crucial differences among the forms of magnesium supplements. However, there is one form that stands way above the others, especially useful if you have heart rhythm disorders, osteoporosis/osteopenia, or muscle cramps: magnesium water that you make yourself. The post Does the form of magnesium matter? appeared first on Dr. William Davis.
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Magnesium arrhythmia cramps heart rhythm disorder magnesium water osteopenia osteoporosis undoctored wheat belly Source Type: blogs
Publication date: Available online 21 March 2019Source: MitochondrionAuthor(s): Hamza El Hadi, Roberto Vettor, Marco RossatoAbstractCardiovascular disease is the leading cause of diabetes-related morbidity and mortality. It is widely accepted that heart failure risk is increased in diabetic patients even after adjusting for coronary artery disease and hypertension. Mitochondria are the center of fatty acid (FA) and glucose metabolism and thus are likely to be impacted by impaired metabolism associated with diabetes. Although the cause of this increased heart failure risk is multifactorial, increasing evidence points toward...
Source: Mitochondrion - Category: Biochemistry Source Type: research
Inflammation may be a predictor for new onset atrial arrhythmias in Takotsubo cardiomyopathy.Europace
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Publication date: April 2019Source: Archives of Cardiovascular Diseases Supplements, Volume 11, Issue 2Author(s): M. Gandon-Renard, F. Lefebvre, D. Courilleau, S. Gomez, P. Gerbaud, A.M. Gomez, J.J. MercadierCardiac ryanodine receptors (RyR2) have a key role in excitation-contraction coupling by releasing Ca2+ from sarcoplasmic reticulum (SR). In cardiomyocytes, 2 FK506 binding protein (FKBP) isoforms have been shown to bind and to stabilize RyR2 opening: FKBP12 and FKBP12.6, the later having a stronger affinity for RyR2 despite its lower abundance. Cardiac-specific FKBP12.6 overexpressing mice have fewer arrhythmias induc...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
ConclusionOur results demonstrate that MCa penetrates adult cardiomyocytes as well as human iPS derived cardiomyocytes and modulates RyR2 activity. MCa analogues exhibit different effects on RyR2, from positive to negative allosteric modulation. These results provide promising evidence that MCa could be used as an in cellulo modulator of RyR2 to control abnormal RyR activity in pathological situations.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Publication date: April 2019Source: Archives of Cardiovascular Diseases Supplements, Volume 11, Issue 2Author(s): V. Dubes, S. Charron Guitoger, C. Michel, M. Constantin, M. Haissaguerre, M. Hocini, O. Bernus, D. BenoistIntroductionThe right ventricular outflow tract (RVOT) is the main origin of idiopathic ventricular tachycardia (IVTs). Sympathetic stimulation is involved in IVTs but mechanisms underlying this preferential origin remain unknown.ObjectiveTo determine the role of ß1- and ß2-adrenergic receptors (ß1-AR, ß2-AR) in the regional modulation of right ventricular (RV) electrophysiological p...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
ConclusionWe have developed new red-shifted VSDs and validate their use in cardiac applications, which might allow optimizing optical mapping of cardiac arrhythmia dynamics in deeper tissue layers and/or in blood-perfused tissues.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
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