New Guidelines on Neuropsychiatric Symptoms in Huntington's New Guidelines on Neuropsychiatric Symptoms in Huntington's

New guidelines for the management of agitation, anxiety, apathy, psychosis, and sleep disorders in Huntington's disease patients have been published.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

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In conclusion, the studies presented in the current review demonstrate that CBD has the potential to limit delta-9-THC-induced cognitive impairment and improve cognitive function in various pathological conditions. Human studies suggest that CBD may have a protective role in delta-9-THC-induced cognitive impairments; however, there is limited human evidence for CBD treatment effects in pathological states (e.g. schizophrenia). In short, they found that CBD may help alleviate the negative impact of a person with schizophrenia from taking cannabis, both in the psychotic and cognitive symptoms associated with schizophrenia. T...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Alternative and Nutritional Supplements Disorders General Research Treatment cannabidiol Cannabis cbd cbd oil Marijuana THC Source Type: blogs
Motor and Nonmotor Symptoms of Parkinson's Disease: Antagonistic Pleiotropy Phenomena Derived from α-Synuclein Evolvability? Parkinsons Dis. 2018;2018:5789424 Authors: Takamatsu Y, Fujita M, Ho GJ, Wada R, Sugama S, Takenouchi T, Waragai M, Masliah E, Hashimoto M Abstract Lewy body diseases, such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), are associated with a wide range of nonmotor symptoms (NMS), including cognitive impairment, depression and anxiety, sleep disorders, gastrointestinal symptoms, and autonomic failure. The reason why such dive...
Source: Parkinsons Disease - Category: Neurology Tags: Parkinsons Dis Source Type: research
We present the case of a 12-year-old child with atypical autism who developed psychotic symptoms that led to a diagnostic dilemma. Proper exploration of early childhood history, prompt treatment with an antipsychotic medication, and social skill training led to resolution of psychotic symptoms and improvement in disruptive symptoms of autism. Keywords: Autism, psychosis, association, autism spectrum disorder, ASD Since the concept of psychosis by Blueler 1 and Kraeplin2 first emerged, autism spectrum disorder (ASD) was thought to be an early manifestation of psychosis or schizophrenia, and ASD in children was referred as &...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Report Current Issue ASD association autism autism spectrum disorder psychosis Source Type: research
This is the 1000th presentation to my bioethics blog since starting on Google Blogspot.com in 2004.There has been many topics covered. Though comments by the visitors has always been encouraged and, since as a " discussion blog " , comments leading to discussions I have felt was the definitive function here. Virtually none of the thread topics have gone unread and most have had some commentary, some with mainly particularly strong and emphatic opinions http://bioethicsdiscussion.blogspot.com/2013/01/should-pathologists-be-physicians.html, some with extensive up to 12 years long continued discussion http://bioethi...
Source: Bioethics Discussion Blog - Category: Medical Ethics Source Type: blogs
DISCUSSION: All comparisons between scale scores and PSG results showed poor or totally absent concordance between subjective and objective measures. SIGNIFICANCE: The subjective evaluation of sleep in HD patients shows a poor correlation with PSG results. PMID: 29169178 [PubMed - as supplied by publisher]
Source: Neuro-Degenerative Diseases - Category: Neurology Authors: Tags: Neurodegener Dis Source Type: research
Discussion: All comparisons between scale scores and PSG results showed poor or totally absent concordance between subjective and objective measures.Significance: The subjective evaluation of sleep in HD patients shows a poor correlation with PSG results.Neurodegener Dis 2017;17:330-337
Source: Neurodegenerative Diseases - Category: Neurology Source Type: research
Abstract Melatonin, through its different receptors, has pleiotropic functions in mammalian brain. Melatonin is secreted mainly by the pineal gland and exerts its effects via receptor-mediated and non-receptor-mediated actions. With recent advancement in neuroanatomical mapping, we may now understand better the localizations of the two G protein-coupled melatonin receptors MT1 and MT2. The abundance of these melatonin receptors in respective brain regions suggests that receptor-mediated actions of melatonin might play crucial roles in the functions of central nervous system. Hence, this review aims to summarize th...
Source: Brain Structure and Function - Category: Neuroscience Authors: Tags: Brain Struct Funct Source Type: research
We report here an overview of the Depression Inventory Development initiative, including results of the third iteration of items assessing symptoms related to anhedonia, cognition, fatigue, general malaise, motivation, anxiety, negative thinking, pain and appetite. The strategies adopted from the Depression Inventory Development program, as an empirically driven and collaborative process for scale development, have provided the foundation to develop and validate measurement tools in other therapeutic areas as well. Introduction The Hamilton Depression Rating Scale (HAMD)[1] and Montgomery–Åsberg Depression Rati...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Depression Mood Disorders Patient Assessment Psychiatry Review Scales Trial Methodology depressive symptoms item response theory major depressive disorder rating scales Source Type: research
Abstract Bruxism is an abnormal repetitive movement disorder characterized by jaw clenching and tooth gnashing or grinding. It is classified into two overlapping types: awake bruxism (AB) and sleep bruxism (SB). Theories on factors causing bruxism are a matter of controversy, but a line of evidence suggests that it may to some extent be linked to basal ganglia dysfunction although so far, this topic has received little attention. The purpose of this article was to review cases of bruxism reported in various movement disorders. The biomedical literature was searched for publications reporting the association of bruxism with...
Source: Journal of Prosthodontics - Category: Dentistry Authors: Tags: Review Source Type: research
After noticing some unusual mental and physical behavior, appointments with and tests by a neurologist, we got the startling diagnosis of Huntington's Disease (HD) in March 2010. It was an unwelcome surprise, as we were not aware that this genetic brain disease was in her father's family. Mary's reaction was, "I don't want to know that..." but now, five years later, she's resigned to her fate. I was glad to know what we were dealing with but had no idea that I would spend my retirement as a 24x7 caregiver. We've been married 54 years and had plans to continue the world travel that began in Japan after our marr...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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