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Hugh Pullen on drug verification, the march of measles, tortoise-inspired technology
Source: FT.com - Drugs and Healthcare - Category: Pharmaceuticals Source Type: news

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The rise of vaccine-preventable illnesses, such as measles and hepatitis, in the United States and around the globe has been alarming in recent years. For women — especially those hoping to become pregnant, as well as women who are pregnant or have recently had a baby — vaccines can be a worrisome topic. There are many misconceptions about vaccine safety in and around pregnancy that can lead to confusion and unnecessary fear of a lifesaving medical tool. As a practicing ob/gyn, I often discuss vaccines with my patients and help them sort out fears versus facts. Which vaccines should you consider before concepti...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Parenting Pregnancy Vaccines Women's Health Source Type: blogs
Conclusion: MeV vaccine is useful and safe as anticancer therapy with a notable impact on the local Iraqi breast cancer AMJ13 cells.
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
I am afraid for Dr. Tedros’ safety. The World Health Organization Director-General and I are walking from the WHO’s midtown-Manhattan offices to the nearby U.N. campus, where Tedros is participating in the U.N. General Assembly. As we cross avenues amid a chorus of honking horns, Tedros is so intent on answering my questions, rarely breaking eye contact, that he appears not to notice traffic lights changing and cyclists whizzing past at alarming proximity. His staff and I breathe a collective sigh of relief when he arrives at the U.N. unscathed. It should come as no surprise that the man at the helm of the worl...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized climate change health World Health Organization Source Type: news
Nanorobots swimming in blood vessels, in silico clinical trials instead of experimenting with drugs on animals and people, remote brain surgeries with the help of 5G networks – the second part of our shortlist on some astonishing ideas and innovations that could give us a glimpse into the future of medicine is ready for you to digest. Here, we’re going beyond the first part with medical tricorders, the CRISPR/Cas-9 gene-editing method, and other futuristic medical technologies to watch for. 11) In silico clinical trials against testing drugs on animals As technologies transform every aspect of healthcare,...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence E-Patients Future of Medicine Future of Pharma Genomics Health Sensors & Trackers 3d printing AI bioprinting blockchain clinical trials CRISPR digital digital health drug development genetics Innovat Source Type: blogs
Ungerechts Engeland Tumor-targeted immunomodulation using oncolytic viral vectors is currently being investigated as a promising strategy in cancer therapy. In a previous study, we showed that a measles virus Schwarz vaccine strain (MeVac) vector encoding an interleukin-12 fusion protein (FmIL-12) is an effective immunotherapy in the MC38cea murine colon adenocarcinoma model. We hypothesized that MeVac encoding interleukin-15 may mediate enhanced T and NK cell responses and thus increase the therapeutic efficacy, especially in NK cell-controlled tumors. Therefore, we generated MeVac vectors encoding an interleuki...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Replication-competent oncolytic viruses (OVs) have been proven to be a potent anticancer weapon for clinical therapy. The preexisting neutralizing antibody in patients is a big challenge for oncolytic efficacy...
Source: Journal of Experimental and Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Research Source Type: research
o R Abstract This chapter describes the development of recombinant oncolytic measles viruses (MeV) that selectively enter and destroy tumor cells. The envelope of MeV is a favorable targeting substrate because receptor attachment and membrane fusion functions are separated on two proteins: the hemagglutinin (H) that binds receptors, and the fusion (F) protein that fuses the viral envelope with the cell membrane. The cell entry process, which depends on receptor recognition and occurs at the plasma membrane at neutral pH, results in the delivery of encapsidated genomes to the cytoplasm, where they replicate. Toward...
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research
Two years after a brain cancer diagnosis and chemotherapy left her with a compromised immune system, student and hockey player Marissa Gootjes hopes New Brunswick will make measles vaccinations mandatory for everyone.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada Source Type: news
Up to one in seven five-year-olds may not be up to date with MMR Related items fromOnMedica Swine flu jab in pregnancy safe for children as well as mothers Parental confidence in immunisation programme ‘very high’ Debate over mandatory MMR vaccination Preventing cervical cancer: how a screening switch and HPV vaccination should cut cancer rates Experts profile four types of vaccine refusers
Source: OnMedica Latest News - Category: UK Health Source Type: news
(Natural News) Even though developed nations boast of great technology, infrastructure, economy, and advanced medical care, they still suffer from ballooning rates of obesity, chronic disease, cardiovascular issues, metabolic disorders, and cancer. Infectious diseases still run rampant in developed nations, despite advances in plumbing and sanitation. The breakdown of developed nations is a slow and...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
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