Benefits and Harms of Anticoagulation in Patients With AF Benefits and Harms of Anticoagulation in Patients With AF

This practice pearl presents decision rules to help determine the risk vs. benefit of anticoagulation therapy in patients with nonvalvular atrial fibrillation.American Family Physician
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

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Authors: Dhamane AD, Baker CL, Rajpura J, Mardekian J, Dina O, Russ C, Rosenblatt L, Lingohr-Smith M, Lin J Abstract Objective: To compare the risk of hospitalization and costs associated with major bleeding (MB) or stroke/systemic embolism (SE) among elderly patients with nonvalvular atrial fibrillation (NVAF) who initiated apixaban then switched to another oral anticoagulant (OAC) vs. those who continued with apixaban treatment. Methods: NVAF patients (≥65 years) initiating apixaban were identified from the Humana database (1/1/2013-9/30/2017) and grouped into Switcher and Continuer cohorts. For Switchers, the...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Conclusions: Trans-apical off-pump MV repair with the NeoChord system is a safe, minimally invasive procedure, with few minor complications. In well-selected candidates it provides successful treatment of degenerative MR. Results are anatomy dependent, so preoperative patient selection is crucial. PMID: 31119000 [PubMed]
Source: Videosurgery and Other Miniinvasive Techniques - Category: Surgery Tags: Wideochir Inne Tech Maloinwazyjne Source Type: research
Death, stroke, and cardiac arrest outcomes are comparable to drug therapy.
Source: AJN - Category: Nursing Tags: In the News Source Type: research
We present a paroxysmal atrial ļ¬brillation (AF) patient who had frequent AF events originating from a persistent left superior vena cava (PLSVC) with an unsuccessful catheter ablation using a non-irrigated radiofrequency catheter and was successfully cured by a successful PLSVC isolation using a second-generation cryoballoon catheter (28-mm, second-generation cryoballoon, Arctic Front Advance, Medtronic, Minneapolis, MN, USA).
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Patients in a study of catheter ablation who showed signs of more injury to nerve cells and glia in the heart had fewer symptoms after the treatment.
Source: The Scientist - Category: Science Tags: News & Opinion Source Type: news
Boston Scientific has initiated a study that will compare the Watchman FLX left atrial appendage (LAA) closure device’s safety and effectiveness to that of anticoagulants for reducing stroke risk in atrial fibrillation patients in a new trial. The randomized, controlled OPTION trial will enroll 1,600 patients with non-valvular AFib who are suitable for oral anticoagulants (OAC) therapy and have recently had or will have an ablation. Patients at as many as 130 global sites will be randomized to receive the newest-generation Watchman FLX device or an OAC, inclusive of commonly prescribed direct oral anticoa...
Source: MDDI - Category: Medical Devices Authors: Tags: Cardiovascular Business Source Type: news
Authors: Albertini F, Struglia M, Faraone V, Fioravanti R, Boursier Niutta S Abstract The peripherally inserted central catheters (PICCs) are third generation silicone or polyurethane catheters, used as venous accesses for long- and medium-term care, and recommended in therapies that require venous access for more than six days. Current implantation methods recommend the radiological method, using standard chest RX in antero-posterior projection, as a method of assessing the correct positioning of the catheter tip. The observational study evaluated the effectiveness in terms of reliability of the intracavitary tip ...
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
CONCLUSIONS: AF ablation is able to decrease the arrhythmic episodes but does not offer a statistically significant protection against the composite of death, disabling stroke, severe bleeding and cardiac arrest In the mid-term follow-up. PMID: 31115243 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
AbstractIntroductionThe 2014 American Heart Association (AHA)/American College of Cardiology (ACC)/Heart Rhythm Society (HRS) guidelines recommend anticoagulation to reduce clot formation and the risk of thromboembolic events in patients with atrial fibrillation but does not specify guidelines for the elderly population. Direct oral anticoagulants (DOACs) are newer US FDA-approved alternatives to warfarin and include dabigatran, rivaroxaban, apixaban and edoxaban. The efficacy of DOACs is heavily researched, but few studies have evaluated their bleeding risk.ObjectivesThis systematic review and meta-analysis investigates w...
Source: Drugs in R&D - Category: Drugs & Pharmacology Source Type: research
Conclusion: Patients with prior stroke may be the preferred group for LAAC regardless of the presence or absence of contraindications for anticoagulant therapy.
Source: Cerebrovascular Diseases - Category: Neurology Source Type: research
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