Hemorrhagic Transformation of Arterial Ischemic and Venous Stroke in Children

Hemorrhagic transformation can complicate both arterial ischemic stroke (AIS) and cerebral sinus venous thrombosis (CSVT). Risk factors for hemorrhagic transformation after adult AIS include larger infarct volume, cardioembolic stroke, and anticoagulation in the acute period. Large hemorrhagic transformation in adults is associated with poor outcome. Therefore, hemorrhagic transformation is used as a safety endpoint of most AIS acute treatment and secondary prevention trials. Up to 30% of children with AIS have hemorrhagic transformation, most of which is petechial.
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Topical Review Source Type: research