P075 vitamin b12 malabsorption and deficiency following restorative proctocolectomy: a systematic review and meta-analysis

Restorative proctocolectomy (RP) is a common surgical procedure utilized in the management of inflammatory bowel disease (IBD), primarily ulcerative colitis (UC). This procedure involves removal of the colon, and the formation of a pouch from the distal portion of the ileum, the primary site for absorption of vitamin B12. Vitamin B12 deficiency has been linked to fatigue, depression, memory loss, weakness, neuropathy, and altered bowel habits. In RP, surgical manipulation of the ileum, an altered microbiota, and pouchitis may potentially impair vitamin B12 status.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Disease Complications Source Type: research

Related Links:

Is there an increased risk of developing de novo inflammatory bowel disease while under treatment with anti-TNF-alpha for other chronic inflammatory or immune-mediated diseases?Alimentary Pharmacology &Therapeutics
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news
The National Institute of Mental Health (NIMH) convened a two-day meeting with researchers and suicide prevention advocates to identify and prioritize research needs in the application of predictive modeling in suicide prevention among healthcare providers. Meeting participants aimed to discuss best practices for developing, implementing, and evaluating these predictive tools in clinical and research settings.
Source: National Institute of Mental Health - Category: Psychiatry Authors: Source Type: news
Publication date: Available online 16 September 2019Source: Carbohydrate PolymersAuthor(s): Kang Liu, Xiang-Li Kong, Qiang-Ming Li, Hai-Lin Zhang, Xue-Qiang Zha, Jian-Ping LuoAbstractA gel delivery system was developed in the present work using whey protein isolate and lotus root amylopectin via regulating pH. The texture, thermodynamics, rheology and microstructure of gels were evaluated. Results showed that pH at 7.0 induced a more compact and stable gel structure than other pH. The composite gel formed at pH 7.0 was accordingly employed to encapsulate vitamin D3. Results exhibited that the encapsulation of composite gel...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: Available online 16 September 2019Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Yifan Yu, Russell Macoon, Anuj ChauhanAbstractDryness and discomfort are considered to be the biggest causes of dropouts in contact lens wearers. We propose a new method to improve lubricity by polymerizing a thin film of a hydrophilic polymer poly-dimethylacrylamide (DMA) on the contact lens. The proposed approach involving soaking the lens in a solution of azobisisobutyronitrile (AIBN) in methanol to load the hydrophobic thermal initiator into the lens. The AIBN-loaded lens is then placed...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
AbstractThe aim of this study was to examine the associations between self-harm and suicidal behavior in indigenous Sami and non-Sami adolescents and mental health and social outcomes in young adulthood. Data were obtained by linking the Norwegian Patient Registry (2008 –2012), the National Insurance Registry (2003–2013), and the Norwegian Arctic Adolescent Health Study, a school-based survey inviting all 10th grade students in North Norway (2003–2005). In total, 3987 (68%) of all 5877 invited participants consented to the registry linkage, of whom 9.2% were indigenous Sami. Multivariable logistic regress...
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
Conclusions: Compared to the individual learning experience, genetic influences seem to play a minor role in explaining variation in placebo analgesia in this experimental paradigm. However, our results are restricted to placebo effects through conditioning on pain in healthy volunteers and should be replicated in larger samples and in patients. Furthermore, potential gene–environment interactions should be further investigated.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion: Our study suggests there are high prevalence rates for mental health and addiction conditions in patients attending the out-of-hours clinic 18 months after the wildfires, with significant associations between multiple variables and likely PTSD, MDD, and GAD. Further studies are needed to explore the impact of population-based mental health interventions on the long-term mental health effects of the wildfires.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
The objective of this study was to determine the acceptability of TMS by psychiatrists and to analyze the factors influencing it. METHOD: A sample of psychiatrists was recruited in order to complete an online quantitative acceptability study using a four variable domain model (utility, intention of use, facility, risk) allowing an acceptability score calculation. RESULT: Four hundreds and seventy-six observations were included in the analysis. Regarding the main objective, the overall TMS acceptability score was high for 47.2% of psychiatrists, average for 40.6% and low for 12.1% of them. The main factors influenci...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
CONCLUSION: I2/Q ratio may provide a consistent quantitative measure of a student's efficiency in assessing suicidal risk. Further research is now needed to evaluate its consistency in other clinical cases. PMID: 31522835 [PubMed - as supplied by publisher]
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
This study is a prospective, exploratory, qualitative analysis. Twenty midwives from Grenoble Alpes University Hospital who took care of one of the selected patients participated in this study. Two women had schizophrenia and one bipolar disorder. Interviews realized with a semi-structured guide were fully transcribed, anonymized and thematically analyzed. Topics have been structured according to the number of occurrences to build a thematic tree. RESULTS: Midwives felt insecure and resourceless when the postpartum care was unclear, insufficiently anticipated and in case of a danger for the women or the children. They ...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
More News: Amnesia | Brain | Depression | Gastroenterology | Inflammatory Bowel Disease | Neurology | Ulcerative Colitis | Vitamin B12 | Vitamin B12 Deficiency | Vitamins