Pattern of Marginal Local Failure in a Phase II Trial of Neoadjuvant Chemotherapy and Stereotactic Body Radiation Therapy for Resectable and Borderline Resectable Pancreas Cancer.

CONCLUSIONS: Neoadjuvant SBRT was well tolerated, however LFs were predominantly observed outside the PTV33 volume that would have been covered with conventional RT volumes. The durability of local control after SBRT in the neoadjuvant setting merits examination relative to chemoradiation before incorporation into routine practice. PMID: 30724781 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30724781?dopt=Abstract

Source: Ann Oncol - February 4, 2019 Category: Cancer & Oncology Authors: Kharofa J, Mierzwa M, Olowokure O, Sussman J, Latif T, Gupta A, Xie C, Patel S, Esslinger H, Mcgill B, Wolf E, Ahmad SA Tags: Am J Clin Oncol Source Type: research