Genome sequences of chikungunya virus isolates circulating in midwestern Brazil

In this study, six CHIKV isolates circulating in midwestern Brazil (Mato Grosso state) were isolated from patient sera, and their complete genomes were sequenced using a high-throughput sequencing platform. All of these isolates shared high nucleotide sequence similarity with CHIKV isolates from northeastern Brazil and were found to belong to the ECSA lineage. These CHIKV isolates did not contain the A226V or L210Q mutations that are associated with increased transmissibility byA. albopictus, suggesting that the CHIKV isolates circulating in midwestern Brazil are predominantly transmitted byA. aegypti.
Source: Archives of Virology - Category: Virology Source Type: research