Is there an association between isotretinoin therapy and adverse mood changes? A prospective study in a cohort of acne patients.

CONCLUSION: The relationship between isotretinoin and depression is the most debated aspect of isotretinoin therapy. Our results link isotretinoin to an overall improvement in psychological wellbeing, even in patients suffering with stable mental illness. However, we also found that a small minority of patients are susceptible to severe mood deterioration, particularly in conjunction with severe physical side effects. PMID: 30717601 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30717601?dopt=Abstract

Source: Journal of Dermatological Treatment - February 7, 2019 Category: Dermatology Tags: J Dermatolog Treat Source Type: research