Kidney Stone Detection? (There ’s an App for That Too)

Mayo Clinic researchers have discovered a way to predict the likelihood that a person might have reoccurring kidney stones. The team’s research was published in Mayo Clinic Proceedings. Data was used from the Rochester Epidemiology Project, where a team of researchers explored a sampling of chronic kidney stones formed from Olmsted County between 1984 and 2017. Some common features of patients who had recurrent stone events included younger age, male sex, a higher body mass index, history of pregnancy, and a family history of stones. The Mayo Clinic team also noted that stone recurrence tended to increase after each subsequent event, and the size and location of stones also associated with the risk of future episodes. "Each of the risk factors we identified are entered into the model, which then calculates an estimate of the risk of having another kidney stone in the next five or 10 years," John Lieske, M.D., one of the study researchers, said in a release. Updating the Recurrence of Kidney Stone model with data collected from the study has improved the tool's ability to predict subsequent events. Since the risk of stone recurrence varies depending on individual factors, this information can be useful for patients or caregivers when deciding how aggressively they want to adopt measures to reduce risk for stone recurrence. The tool, which is available online or as an app, also can be used in research studies to identify those patients most likely to...
Source: MDDI - Category: Medical Devices Authors: Tags: Digital Health Source Type: news

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ConclusionCalprotectin concentrations in amnion fluid and stools serve as potential indicators of inflammatory states during pregnancy. Urinary calprotectin concentrations are continuously high during pregnancy and show no significant variations between trimesters 1 –3 and post-partum.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
There has been a substantial increase in the utilization of imaging, particularly of multi-detector computed tomography (MDCT), for the evaluation of patients with suspected urolithiasis over the past 2  decades. While the diagnostic accuracy of computed tomography (CT) for urolithiasis is excellent, it has also resulted in substantial medical expenditures and increased ionizing radiation exposure. This is especially concerning in patients with known nephrolithiasis and in younger patients. This p ictorial review will focus on recent trends and controversies in imaging of patients with suspected urolithiasis, includin...
Source: Canadian Association of Radiologists Journal - Category: Radiology Authors: Tags: Trauma and Emergency Room Imaging / L'imagerie des urgences et des traumatismes Source Type: research
Rationale: Colorectal cancer (CRC) is the 2nd most common type of cancer in females and the 3rd in males, worldwide. It occurs rarely during pregnancy and is often associated with poor prognosis, due to the unspecific manifestations until advanced stage. Majority of CRC are localized in the rectum (63%) and the sigmoid colon (20%) during pregnancy. Patient concerns: In thisstudy, we report the case of a pregnant woman who was diagnosed with adenocarcinoma of the ascending colon at her 33rd gestational week. She was referred to our department from local hospital with low fever and right-sided flank pain, which had last...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
AbstractAntepartum nephrolithiasis presents a complex clinical scenario which often requires an intervention such as ureteral stent or percutaneous nephrostomy tube (PCNT) placement, especially in the setting of urinary tract infection (UTI). We assess the risk of UTI and preterm labor in the setting of antepartum nephrolithiasis. A retrospective review of an administrative dataset for California and Florida was performed, which included pregnant women admitted for a delivery between 2008 and 2011. Antepartum nephrolithiasis admissions were identified, as were urological intervention (ureteral stent/ureteroscopy) or PCNT p...
Source: Urolithiasis - Category: Urology & Nephrology Source Type: research
Conclusions: The diagnosis of PH should be considered in patients with severe, recurrent calcium oxalate nephrolithiasis. Early treatment with pyridoxine reduces urinary oxalate excretion and can delay progression to end-stage renal disease (ESRD). After ESRD, intensive dialysis is needed to prevent systemic oxalate accumulation and deposition. Combined liver and kidney transplantation is curative. In our patient, we anticipate that liver transplantation will cure both the hyperoxaluria and the hypercoagulable state.Case Rep Nephrol Dial 2018;8:223 –229
Source: Case Reports in Nephrology and Dialysis - Category: Urology & Nephrology Source Type: research
In conclusion, the association between allopurinol and teratogenicity appears to be weak and limited to two reports with uncertain causality. However, the available data are insufficient to make a certain judgement, and as allopurinol treatment evolves, report and prospective follow-up of all exposed infants (i.e. deviant and normal cases) should be encouraged.
Source: Reproductive Toxicology - Category: Toxicology Source Type: research
Purpose of review To identify the latest progression on medical treatment of urinary stones. Recent findings Nonsteroidal anti-inflammatory drugs should be the preferred analgesic option for patients presenting to the emergency department with renal colic. A-blockers could be of patient benefit when used for distal ureteral stones more than 5 mm in size. However, the quality of the randomized controlled studies on medical expulsive therapy (MET) is still low based on the Consolidated Standards for Reporting Trials (CONSORT) criteria. MET should be used with caution in children and pregnant women. In patients with re...
Source: Current Opinion in Urology - Category: Urology & Nephrology Tags: PREVENTION OF UROLOGIC CALCULI - BEHAVIOURAL, DIETARY, AND MEDICAL ASPECTS: Edited by Evangelos Liatsikos and Margaret Pearle Source Type: research
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with ...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs
AbstractWe aimed to compare the outcomes of mini-percutaneous nephrolithotomy (mPNL) and standard PNL techniques in the treatment of renal stones  ≥ 2 cm. The study was designed as a randomized prospective study between January 2016 and April 2017. The patients with a kidney stone ≥ 2 cm were included in the study. Patients who had uncorrectable bleeding diathesis, abnormal renal anatomy, skeletal tract abnormalities, pregnant p atients and pediatric patients (
Source: Urolithiasis - Category: Urology & Nephrology Source Type: research
Urolithiasis complicates an estimated 1/1500 pregnancies and presents a unique challenge for urology and MFM teams. The management options, which include intraureteral stenting, percutaneous nephrostomy (PCN), and ureteroscopy, vary significantly with regard to complication rates, duration of treatment, need for re-treatment postpartum, impact on quality of life and overall costs. This analytic model compares all of these factors between management options to define a dominant strategy based on gestational age at presentation.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Stone Disease: Epidemiology & Evaluation II Source Type: research
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