Sex-specific regulation of cardiac microRNAs targeting mitochondrial proteins in pressure overload

ConclusionWe put forward that the male-specific induction of miRNAs and corresponding downregulation of downstream protein targets involved in mitochondrial metabolism may contribute to sex-specific remodeling in PO-induced LVH.

http://link.springer.com/10.1186/s13293-019-0222-1

Source: Biology of Sex Differences - February 6, 2019 Category: Biology Source Type: research