GSE107275 Regulation of gene expression upon inhibition of ROCK and MLCK in mammary epithelial cells

Contributors : Sirio Dupont ; Silvio BicciatoSeries Type : Expression profiling by arrayOrganism : Homo sapiensTo understand how mechanical cues regulate cell metabolism, we compared early changes in gene expression in Ras-transformed MCF10AtK1 mammary epithelial cells grown in high cytoskeletal tension conditions (plastics) vs. cells grown in low cytoskeletal tension conditions (inhibition of the non-muscle myosin II regulatory kinases ROCK and MLCK with standard small-molecule inhibitors Y27632 and ML7, respectively).Keywords: Expression profiling by array

Source: GEO: Gene Expression Omnibus - February 5, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research