Yoga regimen reduces severity of rheumatoid arthritis symptoms

(IOS Press) According a study published in Restorative Neurology and Neuroscience, eight weeks of intensive yoga practice significantly decreases the severity of physical and psychological symptoms in patients with active rheumatoid arthritis (RA), a debilitating chronic auto-immune inflammatory disease. Marked improvements were seen in the levels of certain inflammatory biomarkers and assessments of functional status and disease activity in patients studied, demonstrating yoga's promotive, preventive, curative, and rehabilitative potential for achieving optimal health.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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The objective of this report was to summarize current knowledge of CC, squamous intraepithelial lesions, and human papillomavirus (HPV) infection in non-HIV immunocompromised women to determine best practices for CC surveillance in this population and provide recommendations for screening. We evaluated those with solid organ transplant, hematopoietic stem cell transplant, and a number of autoimmune diseases. A panel of health care professionals involved in CC research and care was assembled to review and discuss existing literature on the subject and come to conclusions about screening based on available evidence and expe...
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research
Leiming Zhang, Yanan Huang, Chuanhong Wu, Yuan Du, Peng Li, Meiling Wang, Xinlin Wang, Yanfang Wang, Yanfei Hao, Tian Wang, Baofeng Fan, Zhuye Gao, Fenghua Fu
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 21 March 2019Source: Journal of EthnopharmacologyAuthor(s): Jinsong Li, Lei Chen, Jian Xu, Zijian Xie, Yunhui Xu, Pan Jiang, Bingjing Duan, Xiaoxian Huang, Feng Feng, Wenyuan LiuAbstractEthnopharmacological relevancePeriploca forrestii Schltr. (PF) is a traditional folk medicine in China that has been used widely for treating rheumatoid arthritis and traumatic injuries for a long history. Previously, we have roughly demonstrated that the ethanol extract of PF possessed in vitro wound healing potential, and more in depth research deserves to be conducted.Aim of the studyThe present study i...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Rheumatoid arthritis (RA) is associated with significantly diminished health-related quality of life. Patient-reported outcomes (PROs) are considered important in RA; however, some symptoms such as morning joi...
Source: Trials - Category: General Medicine Authors: Tags: Methodology Source Type: research
ConclusionIn Asia ‐Pacific patients, tofacitinib improved signs/symptoms over 24 months. Safety over 92 months was generally consistent with global tofacitinib studies; however, infection IRs were higher in Asia‐Pacific patients.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ConclusionsHigh compliance rates support the use of the daily electronic PRO diary in large RCTs. Despite the anticipated issues, the daily electronic diary is expected to reduce recall bias and improve the quality of PRO data collection.Trial registrationRA-BEAM (NCT01710358) and RA-BUILD (NCT01721057).
Source: Trials - Category: Research Source Type: clinical trials
We studied the effect of 4-methyl-phenyl biguanide, a substance chosen by PASS software (Prediction of Activity Spectra for Substance), on oxidative status and activity of oxidation metabolism enzymes participating in limitation free radical processes (aconitate hydratase, glucose-6-phosphate dehydrogenase, and NADP-isocitrate dehydrogenase) in the heart and blood serum of rats with cardiovascular pathology developing against the background of experimental rheumatoid arthritis. Activity of cardiomyocyte cytolysis markers in rat blood serum was also measured. Normalization of the studied parameters under the influence of th...
Source: Bulletin of Experimental Biology and Medicine - Category: Biology Source Type: research
Joint pain in rheumatoid arthritis (RA) represents a significant health burden. Although RA pain is conventionally thought to result from inflammation, it often persists even after control of inflammation with available therapies, suggesting the additional involvements of non-inflammatory mechanisms. Yet, such mechanisms remain largely unexplored. Our in situ hybridization assays suggested that the immune complex receptor Fc γRI was expressed in a subpopulation of joint sensory neurons. Consistent with this finding, the proportion of joint sensory neurons exhibiting a Ca2+ increase in response to IgG-immune complex (...
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
This study evaluated the efficacy of a single intraperitoneal injection of CA1001 (a novel dual-acting, peripherally restricted kappa/delta opioid agonist) on hyperalgesic nociceptive behaviors in the CFA (Complete Freund's Adjuvant) Model of Inflammatory Arthritis Pain in Rats.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Condition:   Rheumatoid Arthritis Intervention:   Drug: Infliximab [infliximab biosimilar 3] Sponsor:   Pfizer Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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